Research Catalog

Genetic engineering manipulating the mechanisms of life

Title: Genetic engineering [electronic resource] : manipulating the mechanisms of life / Russ Hodge ; foreword by Nadia Rosenthal.
Author: Hodge, Russ, 1961-
Publication: New York : Facts On File, c2009.

Available Online

Details

Description

1 online resource (xx, 219 p.) : ill. (some col.), col. map, ports.

Uniform Title

Genetic engineering (Online)

Alternative Title

Genetic engineering (Online)

Subject

Bibliography (note)

Includes bibliographical references and index.

Access (note)

Access restricted to authorized users.

Contents

From breeding to a science of heredity -- The origins of domestic plants and animals -- The rise of agriculture and domestication -- Early ideas of inheritance -- The girl who gave birth to rabbits -- Heredity and the theory of evolution -- Gregor mendel discovers the laws of heredity -- Classical genetics (1900-1950) -- Cell theory and the discovery of chromosomes -- The rediscovery of mendel's work -- The debate over natural selection -- Chromosomes and heredity -- Sex and the X-Y chromosomes -- Fruit flies and the birth of the modern laboratory -- Gene maps -- Chromosome puzzles -- Maize and "jumping genes" -- "One gene makes one enzyme" -- Molecular genetics: what genes are and how they work (1950-1970) -- Physics stimulates new ways of thinking about genes -- Genes are made of DNA -- The double helix -- RNA is the messenger -- The architecture of genes -- On-off switches for genes -- The flow of information from gene to protein in complex organisms -- The rise of genetic engineering (1970-1990) -- Recombinant DNA -- "Natural" genetic engineering -- Molecular cloning and using bacteria as drug factories -- DNA sequencing -- The polymerase chain reaction (PCR) -- Making and marketing genetically modified plants and animals for food -- Knock outs, knock ins, and other methods to study gene functions -- Beatrice Mintz: a pioneer of mouse genetics -- Transgenic animals and models of human disease -- DNA fingerprinting -- Genetic engineering in the age of genomes -- The complexity of genomes -- Introns and alternative splicing -- Non-coding RNAs -- Quality control: how cells detect defective genes -- RNA knock outs -- Molecular machines -- Conditional mutagenesis -- Other methods of controlling the output of genes -- Molecular medicine and gene therapies -- Personalized medicine in the genome age -- DNA vaccines and t cell therapies -- Ethics and genetic engineering -- Reproductive cloning -- Therapeutic cloning and experiments with human cells -- Genetic testing and concerns about eugenics -- GM foods and the rise of environmental movements -- Owning genes, genomes, and living beings -- A look farther ahead.

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