Research Catalog

Title

First in fly : Drosophila research and biological discovery / Stephanie Elizabeth Mohr.

Author

Mohr, Stephanie Elizabeth, 1971-

Publication

• Cambridge, Massachusetts : Harvard University Press, [2018]
• ©2018

Items in the Library & Off-site

Details

Description

xii, 257 pages : illustrations; 25 cm

Summary

A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. Written by a leader in the Drosophila research community, First in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these "first in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.--

Subject

• Drosophila melanogaster > Genetics
• Drosophila melanogaster > Physiology
• Animal models in research

Bibliography (note)

• Includes bibliographical references (pages 205-248) and index.

Contents

Maps -- Change -- Communication -- Size -- Direction -- Difference -- Defenses -- Behavior -- Coordination -- Continuity -- Epilogue -- Appendix A. How to make a flytrap -- Appendix B. Comparable organs in humans and flies.

Call Number

JFE 19-3942

ISBN

• 9780674971011
• 0674971019

LCCN

• 2017039271
• 40027942721

OCLC

1002823697

Author

Mohr, Stephanie Elizabeth, 1971- author.

Title

First in fly : Drosophila research and biological discovery / Stephanie Elizabeth Mohr.

Publisher

Cambridge, Massachusetts : Harvard University Press, [2018]

Copyright Date

©2018

Type of Content

text

Type of Medium

unmediated

Type of Carrier

volume

Creator/Contributor Characteristics

Gender group: Women

Occupational/field of activity group: Geneticists

Occupational/field of activity group: University and college faculty members

Bibliography

Includes bibliographical references (pages 205-248) and index.

Local Note

AUTH: HARVARD MEDICAL SCHOOL.

Other Form:

Online version: Mohr, Stephanie Elizabeth, 1971- First in fly. Cambridge, Massachusetts : Harvard University Press, 2018 9780674984721 (OCoLC)1024312636

Other Standard Identifier

40027942721

Research Call Number

JFE 19-3942