Research Catalog

Title

Enabling precision medicine : the role of genetics in clinical drug development : proceedings of a workshop / Morgan L. Boname [and four others], rapporteurs ; Forum on Drug Discovery, Development, and Translation ; Roundtable on Genomics and Precision Health, Board on Health Sciences Policy, Health and Medicine Division, the National Academies of Sciences, Engineering, Medicine.

Author

Boname, Morgan L.

Publication

• Washington, DC : the National Academies Press, [2017]
• ©2017

Items in the Library & Off-site

Holdings

Details

Additional Authors

• National Academies of Sciences, Engineering, and Medicine (U.S.). Forum on Drug Discovery, Development, and Translation, issuing body. http://id.loc.gov/vocabulary/relators/isb
• National Academies of Sciences, Engineering, and Medicine (U.S.). Roundtable on Genomics and Precision Health, issuing body. http://id.loc.gov/vocabulary/relators/isb
• Enabling Precision Medicine: the Role of Genetics in Clinical Drug Development (Workshop) (2017 : Washington, D.C.)

Description

xxii, 122 pages : illustrations (some color); 23 cm

Summary

"Those involved in the drug development process face challenges of efficiency and overall sustainability due in part to high research costs, lengthy development timelines, and late-stage drug failures. Novel clinical trial designs that enroll participants based on their genetics represent a potentially disruptive change that could improve patient outcomes, reduce costs associated with drug development, and further realize the goals of precision medicine. On March 8, 2017, the Forum on Drug Discovery, Development, and Translation and the Roundtable on Genomics and Precision Health of the National Academies of Sciences, Engineering, and Medicine hosted the workshop Enabling Precision Medicine: The Role of Genetics in Clinical Drug Development. Participants examined successes, challenges, and possible best practices for effectively using genetic information in the design and implementation of clinical trials to support the development of precision medicines, including exploring the potential advantages and disadvantages of such trials across a variety of disease areas. This publication summarizes the presentations and discussions from the workshop"--Publisher's description.

Subjects

• Personalized medicine
• Pharmacogenetics
• Personalized medicine > Congresses
• Pharmacogenetics > Congresses
• Conference papers and proceedings
• Drug development > Congresses

Genre/Form

Conference papers and proceedings.

Note

• On March 8, 2017, the Forum on Drug Discovery, Development, and Translation (the forum) and the Roundtable on Genomics and Precision Health (the roundtable) of the National Academies of Sciences, Engineering, and Medicine (the National Academies) hosted the workshop Enabling Precision Medicine: The Role of Genetics in Clinical Drug Development

Bibliography (note)

• Includes bibliographical references (pages 93-97).

Contents

Introduction -- Overarching considerations for implementing successful genetics-enabled drug development -- Case studies in precision drug development -- Integrating genetics into the drug development pathway for complex diseases -- Finding innovative ways to integrate genetic research into the drug development process -- Reflecting back and looking forward: key themes and potential next steps in genetics-enabled drug development -- Appendix A: References -- Appendix B: Statement of task and workshop agenda -- Appendix C: Speaker biographical sketches -- Appendix D: Registered attendees.

ISBN

• 9780309462631
• 0309462630
• 9780309462648 (canceled/invalid)
• 0309462649 (canceled/invalid)

OCLC

• on1008596618
• 1008596618
• SCSB-8918967

Owning Institutions

Columbia University Libraries