Research Catalog
Targeting cancer : abstracts of papers presented at the LXXXI Cold Spring Harbor Symposium on Quantitative Biology
- Title
- Targeting cancer : abstracts of papers presented at the LXXXI Cold Spring Harbor Symposium on Quantitative Biology / Editors, David Stewart and Bruce Stillman.
- Author
- Cold Spring Harbor Symposium on Quantitative Biology (81st : 2016 : Cold Spring Harbor, N.Y.)
- Publication
- [Cold Spring Harbor, N.Y.] : Cold Spring Harbor Laboratory, [2016]
- ©2016
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| Status | Format | Access | Call Number | Item Location |
|---|---|---|---|---|
| Text | Request in advance | 570.6 C67 v.81 | Off-site |
Details
- Additional Authors
- Description
- xxi, 368 pages : illustrations (some color), portraits; 27 cm.
- Summary
- The 81st Cold Spring Harbor Symposium focused on Targeting Cancer. The implications of how the underlying science can drive improvements in diagnostic, prognostic, and therapeutic approaches was a major theme throughout the Symposium. The topics covered at the meeting included: Cancer Genes and Genomes; Cancer Pathways; Tumor Cell Biology; Cancer Growth & Progression; Innate & Adaptive Immune Responses; and Enabling Technologies. Several speakers participated in interviews during the course of the Symposium week and transcripts of those videos and the Dorcas Cummings lecture are included.
- Series Statement
- Cold Spring Harbor symposium on quantitative biology, 0091-7451 ; LXXXI
- Uniform Title
- Cold Spring Harbor symposia on quantitative biology (Series) ; v. 81.
- Alternative Title
- Abstracts of papers presented at the LXXXI Cold Spring Harbor Symposium on Quantitative Biology
- Symposium LXXXI
- Subjects
- Genre/Form
- Congress.
- Conference papers and proceedings.
- Note
- "June 1-June 5, 2016."
- Bibliography (note)
- Includes bibliographical references and indexes.
- Language (note)
- Text in English.
- Contents
- Symposium participants -- Foreword. Cancer stem cells : Normal and neoplastic stem cells / Melissa N. McCracken, Benson M. George, Kevin S. Kao, Kristopher D. Marjon, Tal Raveh, and Irving L. Weissman -- Targeting the epithelial-to-mesenchymal transition: the case for differentiation-based therapy / Diwakar R. Pattabiraman and Robert A. Weinberg -- Trimming the vascular tree in tumors: metabolic and immune adaptations / Elizabeth Allen, Rindert Missiaen, and Gabriele Bergers -- Cell of origin and cancer stem cells in tumor suppressor mouse models of Glioblastoma / Sheila R. Alcantara Llaguno, Zuanhua Xie, and Luis F. Parada. Genetics and epigenetics : The enigma of p53 / Guillermina Lozano -- Alterations in three-dimensional organization of the cancer genome and epigenome / Joanna Achinger-Kawecka, Phillippa C. Taberlay, and Susan J. Clark -- COmposition and function of mammalian SWI/SNF chromatin remodeling complexes in human disease / John L. Pulice and Cigall Kadoch -- The essential transcriptional function of BRD4 in acute myeloid leukemia / Jae-Seok Roe and Christopher R. Vakoc. Metabolism : Reexamining how cancel cells exploit the body's metabolic resources : Craig B. Thompson and Wilhelm Palm -- Autophagy, metabolism, and cancer / Jessie Yanxiang Guo and Eileen White -- A time for MYC: metabolism and therapy / Chi V. Dang -- Beyond the oncogene revolution: four new ways to combat cancer / Thorsten Berger, Mary E. Saunders, and Tak W. Mak -- Lipid synthesis is a metabolic liability of non-small cell lung cancer / Robert U. Svensson and Reuben J. Shaw. Targets, vaccines, and therapeutics : Cancer immunogenomics: computational neoantigen identification and vaccine design / Jasreet Hundal, Christopher A. Miller, Malachi Griffith, Obi L. Griffith, Jason Walker, Susanna Kiwala, Aaron Graubert, Joshua McMichauel, Adam Coffman, and Elaine R. Mardis -- Targeting HIF2 in clear cell renal cell carcinoma / Hyejin Cho and William G. Kaelin -- BET bromodomain proteins as cancer therapeutic targets / Shaokun Shu and Kornelia Polyak -- To prime, or not to prime: that is the question / Danielle S. Potter and Anthony Letai -- Genetic dissection of cancer development, therapy response, and resistance in mouse models of breast cancer / Stefano Annunziato, Marco Barazas, Sven Rottenberg, and Jos Jonkers. Microenvironment and metastasis : Tumor-stroma interactions in bone metastasis: molecular mechanisms and therapeutic implications / Hanqiu Zheng, Wenyang Li, and Yibin Kang -- Cancer, oxidative stress, and metastasis / Jennifer G. Gill, Elena Piskounova, and Sean J. Morrison -- RON signaling is a key mediator of tumor progression in many human cancers / Najme Faham and Alana L. Welm -- Physical and chemical gradients in the tumor microenvironment regulate tumor cell invasion, migration, and metastasis / Madeleine J. Oudin and Valerie M. Weaver. Models of cancer : Pathways involved in formation of mammary organoid architecture have keys to understanding drug resistance and to discovery of druggable targets / Saori Furuta and Mina J. Bissell -- Explaining the paucity of intratumoral T cells: a construction out of known entities / Douglas T. Fearon -- Modeling breast cancer intertumor and intratumour heterogeneity using xenografts / Alejandra Bruna, Oscar M. Rueda, and Carlos Caldas -- Challenges and opportunities in modeling pancreatic cancer / Michael E. Feigin and David A. Tuveson. Cancer genomics and tumor heterogeneity : Functional genomic characterization of cancer genomes / Thomas P. Howard, Francisca Vazquez, Aviad Tsherniak, Andrew L. Hong, Mik Rinne, Andrew J. Aguirre, Jesse S. Boehm, and William C. Hahn -- How cancer genomics drives cancer biology: does synthetic lethality explain mutually exclusive oncogenic mutations? / Harold Varmus, Arun M. Unni, and William W. Lockwood -- A pipeline for drug target identification and validation / Eusebio Manchado, Chun-Hao Huang, Nilgun Tasdemir, Darjus F. Tschaharganeh, John E. Wilkinson, and Scott W. Lowe -- SIngle-cell analysis of circulating tumor cells as a window into tumor heterogeneity ? David T. Miyamoto, David T. Ting, Mehmet TOner, Shyamala Maheswaran, and Daniel A. Haber -- Discovery of double-stranded genomic DNA in circulating exosomes / Raghu Kalluri and Valerie S. LeBleu. Summary : Moving closer to victory / Taru Muranen and Joan S. Brugge. Dorcas Cummings lecture : Charles Sawyers. Conversations at the symposium : Gabriele Bergers -- Joan Brugge -- Karen Cichowski -- Susan Clark -- Gerard Evan -- Daniel Haber -- William Kaelin -- Raghu Kalluri -- Scott Lowe -- Guillermina (Gigi) Lozano -- David Lyden -- Elaine Mardis -- Sean Morrison -- Benjamin Neel -- Luis Parada -- Sir Michael Stratton -- David Tuveson -- Christopher Vakoc -- Harold Varmus -- Karen Vousden -- Valerie Weaver -- Robert Weinberg -- Eileen White. Author index. Subject index.
- ISBN
- 9781621822103
- 1621822109
- 9781621822097
- 1621822095
- OCLC
- on1000439809
- 1000439809
- SCSB-9034094
- Owning Institutions
- Columbia University Libraries