Research Catalog

Title

HIV and dementia : proceedings of the NIMH / sponsored conference " Pathogenesis of HIV infection of the brain : impact on function and behavior" ; edited by M.B.A. Oldstone and L. Vitković.

Publication

Berlin ; New York : Springer, [1995], ©1995.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• Oldstone, Michael B. A.
• Vitković, Ljubisa, 1947-
• National Institute of Mental Health (U.S.)

Description

xii, 279 pages : illustrations; 25 cm.

Summary

• The principal objective of this monograph is to inform scientists and educated lay audience of now well-documented involvement of the nervous system in AIDS and the tremendous opportunities for basic neuroscience research in this evolving area. The book includes papers presented at the conference Pathogenesis of HIV Infection of the Brain: Impact on Function and Behavior organized by the National Institute of Mental Health, NIH, USA.
• Recent evidence indicates that HIV infection results in the perturbation of the blood-brain barrier potentially facilitating the entry of HIV into the brain parenchyma and directly causing neuronal dysfunction and ultimate death. In addition, recently established models of AIDS in monkeys, cats, and mice faithfully recapitulate aspects of neuropathophysiology of HIV infection in humans thereby providing new opportunities for research in NeuroAIDS.

Series Statement

Current topics in microbiology and immunology, 0070-217X ; 202

Uniform Title

Current topics in microbiology and immunology ; 202.

Alternative Title

Pathogenesis of HIV infection of the brain : impact on function and behavior

Subjects

• Nerveux central, système > Maladies > Congresses
• Infections à HIV > Congresses

Note

• Pathogenesis of HIV infection of the brain : impact on function and behavior.

Bibliography (note)

• Includes bibliographical references and index.

Contents

• The Pathogenesis of HIV Infections of the Brain / R. T. Johnson -- Neurocognitive Disorders in HIV-1 Infection / I. Grant, R. K. Heaton and J. H. Atkinson / The HNRC Group -- AIDS Dementia Complex and HIV-1 Brain Infection: A Pathogenetic Framework for Treatment and Evaluation / R. W. Price -- Quantitative Neuropathologic Assessment of HIV-1 Encephalitis / C. A. Wiley -- Penetration of Solutes, Viruses, and Cells Across the Blood-Brain Barrier / M. W. Brightman, S. Ishihara and L. Chang -- Cytotoxic T Lymphocytes and HIV-1-Related Neurologic Disorders / S. A. Kalams and B. D. Walker -- Distinct HIV-1 env Sequences Are Associated with Neurotropism and Neurovirulence / C. Power, J. C. McArthur, R. T. Johnson, D. E. Griffin, J. D. Glass, R. Dewey and B. Chesebro -- Role for Astrocytosis in HIV-1-Associated Dementia / L. Vitkovic and A. da Cunha -- Therapeutic Approaches to HIV Infection Based on Virus Structure and the Host Pathogen Interaction / C. D. Pauza and D. N. Streblow --
• Neurobiology of Simian and Feline Immunodeficiency Virus Infections / M. B. Gardner and S. Dandekar -- Selected Models of HIV-Induced Neurological Disease / O. Narayan, S. V. Joag and E. B. Stephens -- Feline Immunodeficiency Virus as a Model for Study of Lentivirus Infection of the Central Nervous System / S. J. Henriksen, O. Prospero-Garcia, T. R. Phillips, H. S. Fox, F. E. Bloom and J. H. Elder -- Transgenic Models to Assess the Neuropathogenic Potential of HIV-1 Proteins and Cytokines / L. Mucke, E. Masliah and I. L. Campbell -- Virus Entry and Release in Polarized Epithelial Cells / R. W. Compans -- Traffic of Hematogenous Cells Through the Central Nervous System / K. C. Williams and W. F. Hickey -- Principles of Cytotoxic T Lymphocyte Induction and Recognition / J. L. Whitton and J. Zhang -- Virus-Neuron-Cytotoxic T Lymphocyte Interactions / G. F. Rall and M. B. A. Oldstone.

ISBN

3540591176

OCLC

ocm33152285

Owning Institutions

Columbia University Libraries