Research Catalog

Title

Carbohydrate modifications in antisense research / Yogesh S. Sanghvi, editor, P. Dan Cook, editor.

Publication

Washington, DC : American Chemical Society, 1994.

Items in the Library & Off-site

Details

Additional Authors

• Sanghvi, Yogesh S., 1956-
• Cook, P. Dan, 1944-
• American Chemical Society. Division of Carbohydrate Chemistry.
• American Chemical Society. Meeting (207th : 1994 : San Diego, Calif.)

Description

viii, 232 pages : illustrations; 24 cm.

Series Statement

ACS symposium series, 0097-6156 ; 580

Uniform Title

ACS symposium series ; 580.

Subject

• Antisense nucleic acids > Congresses
• Oligonucleotides > Derivatives > Congresses
• Carbohydrates > Congresses
• Oligonucleotides, Antisense > chemical synthesis
• Carbohydrates > genetics

Genre/Form

Congress.

Note

• "Developed from a symposium sponsored by the Division of Carbohydrate Chemistry at the 207th National Meeting of the American Chemical Society, San Diego, California, March 13-17, 1994."

Bibliography (note)

• Includes bibliographical references and indexes.

Contents

• 1. Carbohydrates: Synthetic Methods and Applications in Antisense Therapeutics: An Overview / Yogesh S. Sanghvi and P. Dan Cook -- 2. Novel Backbone Replacements for Oligonucleotides / Alain De Mesmaeker, Adrian Waldner, Jacques Lebreton, Valerie Fritsch and Romain M. Wolf -- 3. Synthesis of Nonionic Oligonucleotide Analogues / Joseph A. Maddry, Robert C. Reynolds, John A. Montgomery and John A. Secrist III -- 4. Synthesis and Hybridization Properties of DNA Oligomers Containing Sulfide-Linked Dinucleosides / George Just and Stephen H. Kawai -- 5. 4'-Thio-RNA: A Novel Class of Sugar-Modified [beta]-RNA / Laurent Bellon, Claudine Leydier, Jean-Louis Barascut, Georges Maury and Jean-Louis Imbach -- 6. Hexopyranosyl-Like Oligonucleotides / Piet Herdewijn, Hans De Winter, Bogdan Doboszewski, Ilse Verheggen, Koen Augustyns, Chris Hendrix, Tula Saison-Behmoaras, Camiel De Ranter and Arthur Van Aerschot --
• 7. [alpha]-Bicyclo-DNA: Synthesis, Characterization, and Pairing Properties of [alpha]-DNA-Analogues with Restricted Conformational Flexibility in the Sugar-Phosphate Backbone / M. Bolli, P. Lubini, M. Tarkoy and C. Leumann -- 8. 2',5'-Oligoadenylate Antisense Chimeras for Targeted Ablation of RNA / Paul F. Torrence, Wei Xiao, Guiying Li, Krystyna Lesiak, Shahrzad Khamnei, Avudaiappan Maran, Ratan Maitra, Beihua Dong and Robert H. Silverman -- 9. Branched Nucleic Acids: Synthesis and Biological Applications / R. H. E. Hudson, K. Ganeshan and M. J. Damha -- 10. Anti-Human Immunodeficiency Virus Activity and Mechanisms of Unmodified and Modified Antisense Oligonucleotides / T. Hatta, S.-G. Kim, S. Suzuki, K. Takaki and H. Takaku -- 11. Carboranyl Oligonucleotides for Antisense Technology and Boron Neutron Capture Therapy of Cancers / Raymond F. Schinazi, Zbigniew J. Lesnikowski, Geraldine Fulcrand-El Kattan and David W. Wilson --
• 12. Advances in Automated Chemical Synthesis of Oligoribonucleotides / Nanda D. Sinha and Stephen Fry -- 13. Anti-Human Immunodeficiency Virus Activity of a Novel Class of Thiopurine-Based Oligonucleotides / Rich B. Meyer, Jr., Alexander A. Gall and Vladimir V. Gorn -- 14. New Twists on Nucleic Acids: Structural Properties of Modified Nucleosides Incorporated into Oligonucleotides / Richard H. Griffey, Elena Lesnik, Susan Freier, Yogesh S. Sanghvi, Kelly Teng, Andrew Kawasaki, Charles Guinosso, Patrick Wheeler, Venkatraman Mohan and P. Dan Cook.

ISBN

0841230560

LCCN

94038930

OCLC

• 31329044
• ocm31329044

Owning Institutions

Columbia University Libraries