Research Catalog

Title

Bacterial invasiveness / edited by V.L. Miller.

Publication

Berlin ; New York : Springer, [1996], ©1996.

Items in the Library & Off-site

Holdings

Details

Additional Authors

Miller, Virginia L.

Description

vi, 115 pages : illustrations; 24 cm.

Summary

• Bacterial invasion has been a very active area of research due to the extensive amount of morbidity and mortality that can be attributed to this group of pathogens.
• Analysis of many of these pathogens is hampered because they are either obligate intracellular pathogens or because genetic tools to dissect the process have not been available. Nevertheless, a number of invasive bacteria have been studied in considerable detail, and the knowledge gained from these studies serves as a model for future research.
• Invasion (and intracellular survival where appropriate) by the bacteria covered in this volume Yersinia, Shigella, Salmonella, Listeria, enteropathogenic Escherichia coli, and Legionella pneumophila has been studied at the molecular, genetic, and cellular levels.
• The information derived from these diverse approaches is integrated in this volume into a cohesive picture. In recent years the entry steps have been described at the molecular and genetic level, and the important signal transduction events are still being elucidated. When first studied, the entry steps taken by these diverse bacteria seemed to be quite similar, while the genetic basis of entry seemed to be dissimilar.
• However, as more has been learned, we find both similarities and differences at all levels. Many interesting questions remain to be answered and these reviews of the "state of the art" provide a foundation from which to proceed.

Series Statement

Current topics in microbiology and immunology, 0070-217X ; 209

Uniform Title

Current topics in microbiology and immunology ; 209.

Subject

• Bacteria > pathogenicity
• Bacterial Infections > genetics
• Genetics, Microbial

Bibliography (note)

• Includes bibliographical references and index.

Contents

Uptake of Enteropathogenic Yersinia by Mammalian Cells / R.R. Isberg -- Invasion and the Pathogenesis of Shigella Infections / C. Parsot and P.J. Sansonetti -- Molecular and Cellular Bases of Salmonella Entry Into Host Cells / J.E. Galan -- Molecular and Genetic Determinants Involved in Invasion of Mammalian Cells by Listeria monocytogenes / S. Dramsi, M. Lebrun and P. Cossart -- Entry of Enteropathogenic Escherichia coli into Host Cells / M.S. Donnenberg -- Legionella pneumophila Invasion of Mononuclear Phagocytes / H.A. Shuman and M.A. Horwitz.

ISBN

3540600655

OCLC

ocm34247332

Owning Institutions

Columbia University Libraries