Research Catalog

Title

Cytokines : a practical approach / edited by Francis R. Balkwill.

Publication

Oxford ; New York : IRL Press at Oxford University Press, 1995.

Items in the Library & Off-site

Holdings

Details

Additional Authors

Balkwill, Frances R.

Description

xxxiii, 417 pages : illustrations; 24 cm.

Summary

• Cytokines are important regulators of cellular communication, playing a central role in tissue development and repair, immunity and inflammation. They are also implicated in the pathophysiology of many infectious, autoimmune, and malignant diseases, and form the basis of novel therapeutic approaches. Their production is subject to complex and strict control, with local generation of a network of transiently induced cytokines.
• Cytokines: A Practical Approach contains up-to-date methods for the study of cytokines, their receptors, and cytokine-driven processes, together with an overview of current cytokine biology. It provides a detailed research guide to the cloning, identification, characterization, and assay of cytokines, presenting key methods in molecular and cell biology, biochemistry, and immunology.

Series Statement

The Practical approach series ; 155

Uniform Title

Practical approach series ; 155.

Subjects

• Cytokines
• Cytokines > Research > Methodology

Bibliography (note)

• Includes bibliographical references and index.

Contents

• 1. Cloning and expression of cytokine genes / R. Contreras, J. Demolder and W. Fiers -- 2. Southern blotting of cytokine genes / M. O. Diaz and T. W. McKeithan -- 3. Northern analysis, ribonuclease protection, and in situ analysis of cytokine messenger RNA / M. Stuart Naylor, Michele Relf and Frances R. Balkwill -- 4. Polymerase chain reaction to quantitate cytokine mRNA / Cornelia Platzer and Thomas Blankenstein -- 5. Comparative polymerase chain reaction / Sylvie de Kossodo -- 6. Receptor-binding studies / Thomas M. Mariano, Lara Izotova and Sidney Pestka -- 7. Measurement of cytokine induction of PC-specific phospholipase C and sphingomyelinases / Stefan Schutze and Martin Kronke -- 8. Two-dimensional gel electrophoresis for purification, sequencing, and identification of cytokine-induced proteins in normal and malignant cells / Diana M. Smith, Huu M. Tran and Lois B. Epstein -- 9. Antiviral activity of cytokines / John A. Lewis --
• 10. Assays for human B cell responses to cytokines / Robin E. Callard, Karolena T. Kotowicz and Susan H. Smith -- 11. T cells and cytokines / S. B. A. Cohen, J. Clayton, M. Londei and M. Feldmann -- 12. The generation and quantitation of cell-mediated cytotoxicity / Elizabeth Grimm and William Loudon -- 13. Assays for chemotaxis / Jo Van Damme and Rene Conings -- 14. Cytokine regulation of endothelial cells / P. Allavena, E. Dejana, F. Bussolino, A. Vecchi and A. Mantovani -- 15. Biological assays for haemopoietic growth factors / N. G. Testa, C. M. Heyworth, B. I. Lord and E. A. de Wynter -- 16. Assays for macrophage activation by cytokines / Anthony Doyle, Michael Stein, Satish Keshav and Siamon Gordon -- 17. Measurement of proliferative, cytolytic, and cytostatic activity of cytokines / Frances Burke, Enrique Rozengurt and Frances R. Balkwill -- 18. Production of cytokine transgenic and knockout mice / Manolis Pasparakis and George Kollias --
• 19. Development of antibodies to cytokines / S. Poole -- 20. Visualizing the production of cytokines and their receptors by single human cells / C. E. Lewis and A. Campbell -- 21. Quantitative biological assays for individual cytokines / Meenu Wadhwa, Christopher Bird, Lisa Page, Anthony Mire-Sluis and Robin Thorpe -- 22. RIA, IRMA, and ELISA assays for cytokines and their soluble receptors / A. Meager -- A1. Suppliers of specialist items.

ISBN

0199635668 (pbk.)

LCCN

95004092

OCLC

• 32012414
• ocm32012414

Owning Institutions

Columbia University Libraries