Research Catalog

Title

Ribonucleases : structures and functions / edited by Giuseppe D'Alessio, James F. Riordan.

Publication

San Diego : Academic Press, [1997], ©1997.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• D'Alessio, Giuseppe.
• Riordan, James F., 1934-

Description

xix, 670 pages : illustrations (some color); 24 cm

Summary

Pancreatic ribonuclease, the focus of highly productive scientific research for more than half a century and the only enzyme to be the basis of four Nobel prizes, has recently undergone a resurgence in popularity for the recognition of an extended ribonuclease superfamily with functions ranging from tumor growth and inhibition to self-recognition and neurotoxicity. This volume highlights the functional diversity of ribonucleases and reveals the emerging research opportunities provided by these enzymes.

Subject

• Ribonucleases > Structure-activity relationships
• Ribonucleases

Bibliography (note)

• Includes bibliographical references and index.

Contents

• 1. Escherichia coli Ribonucleases: Paradigms for Understanding Cellular RNA Metabolism and Regulation / Allen W. Nicholson -- 2. Barnase and Barstar / Robert W. Hartley -- 3. RNase T[subscript 1]/RNase T[subscript 2] Family RNases / Masachika Irie -- 4. Structure and Mechanism of Action of Cytotoxic Ribonuclease [alpha]-Sarcin / Ira G. Wool -- 5. Plant Ribonucleases / Pauline A. Bariola and Pamela J. Green -- 6. S-RNases and Other Plant Extracellular Ribonucleases / Simon K. Parry, Ying-hong Liu and Adrienne E. Clarke [et al.] -- 7. Evolutionary Reconstructions in the Ribonuclease Family / Steven A. Benner, Mauro I. Ciglic and Monika Haugg [et al.] -- 8. Evolution of Vertebrate Ribonucleases: Ribonuclease A Superfamily / Jaap J. Beintema, Heleen J. Breukelman and Antonella Carsana [et al.] -- 9. Pancreatic Ribonucleases / Claudi M. Cuchillo, Maria Vilanova and M. Victoria Nogues -- 10. Crystallographic Studies of Ribonuclease Complexes / Gary L. Gilliland --
• 11. NMR Solution Structures of Ribonuclease A and Its Complexes with Mono- and Dinucleotides / Carlos Gonzalez, Jorge Santoro and Manuel Rico -- 12. Seminal Ribonuclease: The Importance of Diversity / Giuseppe D'Alessio, Alberto Di Donato and Lelio Mazzarella [et al.] -- 13. Eosinophil-Associated Ribonucleases / Melissa R. Snyder and Gerald J. Gleich -- 14. Structure and Function of Angiogenin / James F. Riordan -- 15. Antitumor RNases / Richard J. Youle and Giuseppe D'Alessio -- 16. 2-5A-Dependent RNase L: A Regulated Endoribonuclease in the Interferon System / Robert H. Silverman -- 17. RNA-Processing RNases in Mammalian Cells / Jeff Ross -- 18. Messenger RNA Ribonucleases and mRNA Turnover in Saccharomyces cerevisiae / Christine E. Brown and Alan B. Sachs -- 19. Ribonuclease Inhibitor / Jan Hofsteenge.

ISBN

0125889453 (alk. paper)

LCCN

96041839

OCLC

ocm35521671

Owning Institutions

Columbia University Libraries