Research Catalog

Title

mRNA metabolism and post-transcriptional gene regulation / editors, Joe B. Harford, David R. Morris.

Publication

New York : Wiley-Liss, [1997], ©1997.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• Harford, Joe B.
• Morris, David R., 1939-

Description

xii, 354 pages : illustrations; 26 cm.

Summary

• mRNA Metabolism and Post-Transcriptional Gene Regulation is the first comprehensive overview of the various modes of gene regulation that exist post-transcriptionally. Collecting studies by some of the top researchers in the field, this volume provides both an up-to-date review of the complex "life" of an mRNA molecule and an introduction to current work on the diversity of mechanisms of post-transcriptional reactions.
• A timely contribution to the understanding of genetic regulatory mechanisms, mRNA Metabolism and Post-Transcriptional Gene Regulation provides a basis from which potential therapeutic strategies may be developed. This book will be of vital interest to cell and molecular biologists at all levels, from graduate students to senior investigators, clinical researchers, and professionals in the pharmaceutical and biotechnology industries.

Series Statement

Modern cell biology ; v. 17

Uniform Title

Modern cell biology ; v. 17.

Subject

• Messenger RNA
• Genetic regulation

Note

• Includes index.

Contents

• Preface / Joe B. Harford and David R. Morris -- RNA Structure / Elisabetta Viani Puglisi and Joseph D. Puglisi -- Transcription and Transcriptional Control: An Overview / Ivan Olave, Ronny Drapkin and Danny Reinberg -- Constitutive and Alternative mRNA Splicing / Sanford I. Bernstein and Dianne Hodges -- Mammalian RNA Editing / Lawrence Chan and Kazuko Nishikura -- mRNA Polyadenylation: Functional Implication / Ellen J. Baker -- RNA Export from the Nucleus / Lynne E. Maquat -- The Intracellular mRNA Sorting System: Postal Codes, Zip Codes, Mail Bags and Mail Boxes / Oswald Steward and Robert H. Singer -- The Fundamentals of Translation Initiation / Han-kuei Huang and Thomas F. Donahue -- cis-Acting mRNA Structures in Gene-Specific Translational Control / David R. Morris -- Mechanisms of mRNA Turnover in Eukaryotic Cells / Sundaresan Tharun and Roy Parker -- Control of mRNA Decay in Plants / Ambro van Hoof and Pamela J. Green --
• Ribonucleases Involved in Eukaryotic mRNA Turnover / Daniel R. Schoenberg and Elena Chernokalskaya -- Characterization of the Nonsense-Mediated mRNA Decay Pathway and Its Effect on Modulating Translation Termination and Programmed Frameshifting / Youmin Weng, Maria Jesus Ruiz-Echvarria and Shuang Zhang [et al.] -- mRNA Metabolism and Cancer / Marcus J. Korth and Michael G. Katze -- Translational Regulation in Animal Virus-Infected Cells / Robert J. Schneider -- RNA Decay by the Interferon-Regulated 2-5A System as a Host Defense Against Viruses / Robert H. Silverman and Nick M. Cirino -- Control of mRNA Stability During Herpes Simplex Virus Infection / G. Sullivan Read -- Regulation of mRNA Expression in HIV-1 and Other Retroviruses / Barbara K. Felber.

ISBN

0471142069 (alk. paper)

LCCN

96039030

OCLC

• 35657866
• ocm35657866

Owning Institutions

Columbia University Libraries