Research Catalog
The combinatorial index
- Title
- The combinatorial index / Barry A. Bunin.
- Author
- Bunin, Barry A.
- Publication
- San Diego : Academic Press, [1998], ©1998.
Items in the Library & Off-site
Filter by
1 Item
Status | Format | Access | Call Number | Item Location |
---|---|---|---|---|
Text | Request in advance | RS419 .B86 1998 | Off-site |
Holdings
Details
- Description
- xvii, 322 pages : illustrations; 26 cm
- Summary
- Combinatorial chemistry has become a major focus of research activity for pharmaceutical, agrochemical, and biotechnology companies. The explosion of combinatorial methods has created the need for a compendium of reliable synthetic transformations from the primary literature. The Combinatorial Index fills this need. Included are chapters on linkers, solid-phase synthetic methods, analytical techniques, and solution libraries.
- Procedures from the literature for constructing combinatorial libraries of small molecules comprise an indispensable laboratory reference for the synthetic chemist. Each procedure in the compilation is preceded by a section entitled "Points of Interest," which highlights the strengths and limitations of the various methods. A structural appendix covers both functional group transformations and heterocyclization reactions in solid-phase synthesis.
- This comprehensive but easy-to-access guide to the combinatorial chemistry literature will save time on tedious library searches, introduce a growing audience of chemists to this exciting field, and lower the barriers to attempting a new or related methodology.
- Subject
- Bibliography (note)
- Includes bibliographical references and indexes.
- Contents
- 1. Introduction -- 2. Background -- 3. Linkers for Solid-Phase Synthesis -- 4. Combinatorial Solid-Phase Synthesis -- 5. Analytical Methods for Solid-Phase Synthesis -- 6. Preparation of Solution Libraries and Combined Approaches at the Solution/Solid-Phase Interface -- App. 1. Summary of Functional Group Transformations for Combinatorial Solid-Phase Synthesis -- App. 2. Classification of Heterocyclization Reactions -- App. 3. Unnatural Biopolymers -- App. 4. Oligosaccharides -- App. 5. List of Abbreviations.
- ISBN
- 0121413403
- LCCN
- 97081368
- OCLC
- ocm38847491
- Owning Institutions
- Columbia University Libraries