Research Catalog

Title

When cells die : a comprehensive evaluation of apoptosis and programmed cell death / edited by Richard A. Lockshin, Zahra Zakeri, and Jonathan L. Tilly.

Publication

New York : Wiley-Liss, [1998], ©1998.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• Lockshin, R. A. (Richard A.)
• Zakeri, Zahra, 1952-
• Tilly, Jonathan L., 1962-

Description

xix, 504 pages : illustrations; 25 cm

Summary

• When Cells Die establishes a coherent framework for the study of cell death - cutting across viewpoints and disciplines and consolidating disparate research efforts.
• Leading international researchers describe a wide range of topics, including evaluation methods for programmed cell death and apoptosis in numerous tissues and circumstances; genetic mechanism, signal transduction, and observed manifestations of physiological cell death; model systems ranging from nematodes to humans; relevant work in cancer research, AIDS, immune disorders, fertility, eye disease, and Alzheimer's disease; and more.
• When Cells Die offers a comprehensive introduction to an intriguing discipline, insight into areas in need of exploration, and information on new techniques and therapeutic applicationsall supported with diagrams and flowcharts and a fully cross-referenced and indexed text. It is important reading for anyone working in cell and developmental biology, neuroscience, immunology, cancer research, and virology.
• It is also useful for advanced undergraduate and graduate-level students, postdoctoral fellows, and researchers just entering the field.

Subject

• Apoptosis > physiology

Bibliography (note)

• Includes bibliographical references and index.

Contents

• Pt. I. The Phenomenon of Cell Death. 1. The Evolutionary Origin and Role of Programmed Cell Death in Single-Celled Organisms: A New View at Executioners, Mitochondria, Host-Pathogen Interactions, and the Role of Death in the Process of Natural Selection / Jean Claude Ameisen. 2. The Reactions of Cells to Lethal Injury: Oncosis and Necrosis - the Role of Calcium / Benjamin F. Trump and Irene K. Berezesky. 3. The Study of Cell Death by the Use of Cellular and Developmental Models / Zahra Zakeri. 4. Genetic Approaches to Programmed Cell Death in C. elegans / Anton Gartner and Michael O. Hengartner. 5. Cell Death in Plants / Ron Mittler -- Pt. II. Themes and Approaches to Cell Death. 6. The Cutting Edge: Caspases in Apoptosis and Disease / Vincent L. Cryns and Junying Yuan. 7. Endonuclease Activities and Apoptosis / Marianna Sikorska and P. Roy Walker -- Pt. III. Cell Death When Mitosis is High and Evanescence is Desirable.
• 8. Apoptotic Signaling Pathways in Lymphocytes / Barbara A. Osborne. 9. Regulation of Immune Responses by Immune Directed Cell Death / M. Karen Newell and Michael S. Vincent. 10. Apoptosis in Autoimmunity / Ralph C. Budd. 11. AIDS and Cell Death / Terri H. Finkel and Carolyn R. Casella -- Pt. IV. Cell Death in Long-Lived Cells. 12. Apoptosis of Tissues of the Eye During Development and Disease / David S. Papermaster. 13. Signal Transduction and Neuronal Cell Death During Development and Disease / Raymond B. Birge, J. Eduardo Fajardo and Barbara L. Hempstead. 14. Cell Death in Alzheimer's Disease / Cari W. Cotman, David H. Cribbs and Christian J. Pike [et al.]. 15. Regulation of Apoptosis by Cellular Interactions with the Extracellular Matrix / James G. Tidball and Douglas E. Albrecht -- Pt. V. The Clinical Relevance of Apoptosis. 16. Cell Death and Species Propagation: Molecular and Genetic Aspects of Apoptosis in the Vertebrate Female Gonad / Jonathan L. Tilly.
• 17. Assessment of Apoptosis in Tumor Growth: Importance in Clinical Oncology and Cancer Therapy / Luis Benitez-Bribiesca.

ISBN

0471165697 (cloth : alk. paper)

LCCN

97023884

OCLC

ocm37214040

Owning Institutions

Columbia University Libraries