Research Catalog

What's wrong with my mouse? : behavioral phenotyping of transgenic and knockout mice

Title
What's wrong with my mouse? : behavioral phenotyping of transgenic and knockout mice / Jacqueline N. Crawley.
Author
Crawley, Jacqueline N.
Publication
New York : Wiley-Liss, [2000], ©2000.

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TextRequest in advance QP356.22 .C73 2000Off-site

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Description
xiii, 329 pages : illustrations; 26 cm
Summary
  • "Transgenic and knockout mutations provide an important means for understanding gene function, as well as for developing therapies for genetic diseases. This book discusses the many advances in the field of transgenic technology that have enabled researchers to bring about various changes in the mouse genome. Equal emphasis is given to both the principles of transgenic and knockout methods and their applications.
  • A clear and concise format provides researchers with a comprehensive review of the behavioral paradigms appropriate for analyzing mouse phenotypes." "Researchers in neuroscience, pharmacology, genetics, developmental biology, and cell biology will all find this book essential reading."--BOOK JACKET.
Subject
  • Neurogenetics > Animal models
  • Transgenic mice > Behavior
Note
  • "Published simultaneously in Canada"--T.p. verso.
Bibliography (note)
  • Includes bibliographical references (p. 253-313) and index.
Contents
Ch. 1. Designer Mice -- Ch. 2. Of Unicorns and Chimeras -- Ch. 3. General Health -- Ch. 4. Motor Functions -- Ch. 5. Sensory Abilities -- Ch. 6. Learning and Memory -- Ch. 7. Feeding and Drinking -- Ch. 8. Reproductive Behaviors -- Ch. 9. Social Behaviors -- Ch. 10. Emotional Behaviors -- Ch. 11. Reward -- Ch. 12. The Next Generation.
ISBN
0471316393 (cloth : acid-free paper)
LCCN
99028955
OCLC
  • ocm41156560
  • SCSB-3863774
Owning Institutions
Columbia University Libraries