Research Catalog
Recombinant antibodies for cancer therapy : methods and protocols
- Title
- Recombinant antibodies for cancer therapy : methods and protocols / edited by Martin Welschof and Jürgen Krauss.
- Publication
- Totowa, N.J. : Humana Press, [2003], ©2003.
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1 Item
| Status | Format | Access | Call Number | Item Location |
|---|---|---|---|---|
| Text | Request in advance | RC271.I45 R43 2003 | Off-site |
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Details
- Additional Authors
- Description
- xiv, 481 pages : illustrations; 24 cm.
- Series Statement
- Methods in molecular biology ; v. 207
- Uniform Title
- Methods in molecular biology (Clifton, N.J.) ; v. 207.
- Subjects
- Antineoplastic Protocols
- Immunoglobulin Fragments > therapeutic use
- Antibodies > immunology
- Antibodies > therapeutic use
- Neoplasms > immunology
- Recombinant antibodies > Laboratory manuals
- Cancer > Immunotherapy
- Antigens, Neoplasm > immunology
- Neoplasms > therapy
- Immunotherapy > methods
- Recombinant Proteins > therapeutic use
- Bibliography (note)
- Includes bibliographical references and index.
- Contents
- Pt. I. Introduction. 1. Generation of Antibody Molecules Through Antibody Engineering / Sergey M. Kipriyanov. 2. Application of Recombinant Antibodies in Cancer Patients / Jurgen Krauss, Michaela Arndt and Michael Pfreundschuh -- Pt. II. Hybridoma-Derived Antibodies. 3. DNA Immunization as a Means to Generate Antibodies to Proteins / Partha S. Chowdhury. 4. Chimerization of a Monoclonal Antibody for Treating Hodgkin's Lymphoma / Jurgen Krauss, Hans Heinrich Forster, Barbara Uchanska-Ziegler and Andreas Ziegler. 5. Humanization of Monoclonal Antibodies by CDR Grafting / Siobhan O'Brien and Tarran Jones -- Pt. III. Recombinant Antibody Fragments from Phagemid-Displayed Antibody Repertoires. 6. Generation and Screening of a Modular Human scFv Expression Library from Multiple Donors / Martin Welschof, Christiane Christ, Ingrid Hermes, Armin Keller, Christian Kleist and Michael Braunagel. 7. Construction of Semisynthetic Antibody Libraries / Michael Braunagel.
- 8. Single-Domain V[subscript H] Antibody Fragments from a Phage Display Library / Liat Binyamin, Daniel Plaksin and Yoram Reiter. 9. Isolation of Human Fab Fragments Against Ovarian Carcinoma Using Guided Selection / Mariangela Figini, Andrew Green, Francesco Colotta and Silvana Canevari. 10. Human Recombinant Fab Antibodies with T-Cell Receptor-Like Specificities Generated from Phage Display Libraries / Jan Engberg, Ali F. Venidunya, Rikke Clausen, Liselotte B. Jensen, Peter Sorensen, Pernille Kops and Erik Riise. 11. Engineering Hot Spots for Affinity Enhancement of Antibodies / Partha S. Chowdhury. 12. Simultaneous Humanization and Affinity Optimization of Monoclonal Antibodies / Herren Wu. 13. Tailoring Kinetics of Antibodies Using Focused Combinatorial Libraries / Herren Wu and Ling-Ling An -- Pt. IV. Antibody Fragments with Additional Properties. 14. Engineering scFvs for Improved Stability / Partha S. Chowdhury and George Vasmatzis.
- 15. Recombinant Single-Chain and Disulfide-Stabilized Fv Immunotoxins for Cancer Therapy / Ravital Niv, Dina Segal and Yoram Reiter. 16. Generation of Recombinant Immunotoxins for Specific Targeting of Tumor-Related Peptides Presented by MHC Molecules / Cyril J. Cohen, Galit Denkberg, Dina Segal and Yoram Reiter. 17. Construction and Characterization of RNase-Based Targeted Therapeutics / Dianne L. Newton, Junichiro Futami, Dale Ruby and Susanna M. Rybak. 18. Bispecific Diabodies for Cancer Therapy / Michaela Arndt and Jurgen Krauss. 19. Generation and Characterization of Bispecific Tandem Diabodies for Tumor Therapy / Sergey M. Kipriyanov. 20. Generation of Recombinant Multimeric Antibody Fragments for Tumor Diagnosis and Therapy / Barbara E. Power, Alexander A. Kortt and Peter J. Hudson. 21. Construction and Characterization of Minibodies for Imaging and Therapy of Colorectal Carcinomas / Paul J. Yazaki and Anna M. Wu.
- 22. Generation, Expression, and Monitoring of Recombinant Immune Receptors for Use in Cellular Immunotherapy / Andreas Hombach, Claudia Heuser and Hinrich Abken. 23. Tailoring Natural Effector Functions: Antibody Engineering Beyond Humanization / Ole H. Brekke and John E. Thommesen. 24. Single-Chain Fv-Based Affinity Purification of the Cellular Stress Protein gp96 for Vaccine Development / Christian Kleist, Daniele Arnold-Schild, Martin Welschof, Martina Finger, Gerhard Opelz, Hans-Georg Rammensee, Hansjorg Schild and Peter Terness. 25. Recombinant Adenoviruses for In Vivo Expression of Antibody Fragments / Roland E. Kontermann, Tina Korn and Valerie Jerome -- Pt. V. Large Scale Production of Recombinant Antibodies for Clinical Application. 26. Production of Antibody Fragments in a Bioreactor / Halldis Hellebust. 27. Large Scale Production of Recombinant Antibodies by Utilizing Cellulose-Binding Domains / Itai Benhar and Yevgeny Berdichevsky.
- 28. Production of Tumor-Specific Antibodies in Tobacco / Carmen Vaquero-Martin and Rainer Fischer.
- ISBN
- 0896039188 (alk. paper)
- LCCN
- 2002067889
- OCLC
- ocm49576679
- SCSB-4309619
- Owning Institutions
- Columbia University Libraries