Research Catalog

Transgenic mouse methods and protocols

Title
Transgenic mouse methods and protocols / edited by Marten H. Hofker, Jan van Deursen.
Publication
Totowa, N.J. : Humana Press, [2003], ©2003.

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TextRequest in advance QH442.6 .T724 2003Off-site

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Details

Additional Authors
  • Hofker, Marten H. (Marten Harro)
  • Deursen, Jan van, 1930-
Description
xiii, 374 pages, 4 unnumbered pages of plates : illustrations (some color); 24 cm.
Series Statement
Methods in molecular biology ; 209
Uniform Title
Methods in molecular biology (Clifton, N.J.) ; v. 209.
Subjects
Genre/Form
Laboratory Manual.
Bibliography (note)
  • Includes bibliographical references and index.
Contents
  • Introduction: The Use of Transgenic Mice in Biomedical Research / Marten H. Hofker -- Genetic Modification of the Mouse: General Technology; Pronuclear and Blastocyst Injection / J. Willem Voncken -- In Vitro Fertilization/Cryopreservation / Susan Marschall and Martin Hrabe de Angelis -- Transgene Design / J. Willem Voncken -- Generating Conditional Mouse Mutants via Tetracycline-Controlled Gene Expression / Kai Schonig and Hermann Bujard -- Manipulating Large Insert Clones for Transgenesis / Sally P. A. McCormick, Catherine Y. Y. Liu, Stephen G. Young and Lars B. Nielsen -- Reporter Molecules in Genetically Engineered Mice / Thomas L. Saunders -- Gene Targeting in Mouse Embryonic Stem Cells / Jan van Deursen -- Conditional Knockout Mice / Ralf Kuhn and Frieder Schwenk -- Knockin Approaches / Anton J. M. Roebroek, Xiaosheng Wu and Richard J. Bram --
  • Aggregation of Embryos and Embryonic Stem Cells / Ronald Maatman, Marina Gertsenstein, Emile de Meijer, Andras Nagy and Kristina Vintersten -- Andenovirus-Mediated Gene Transfer / Ko Willems van Dijk, Kyriakos E. Kypreos, Christine d'Oliveira and Frits J. Fallaux -- Random ENU Mutagenesis / Dian Soewarto, Veronique Blanquet and Martin Hrabe de Angelis -- Autopsy and Histologic Analysis of the Transgenic Mouse / Marion J. J. Gijbels and Menno P. J. de Winther -- Bone Marrow Transplantations to Study Gene Function in Hematopoietic Cells / Menno P. J. de Winther and Peter Heeringa -- Quantification of Atherosclerosis in Mice / Alan Daugherty and Stewart C. Whitman -- Genetically Modified Mice in Cancer Research / David A. Largaespada -- Neuropathobiology in Transgenic Mice: The Case of Alzheimer's Disease / Jo Van Dorpe, Kurt Spittaels, Chris Van den Haute, Ilse Dewachter, Dieder Moechars, Hugo Geerts and Fred Van Leuven.
ISBN
0896039153 (alk. paper)
LCCN
2002068581
OCLC
  • ocm50002670
  • SCSB-4327479
Owning Institutions
Columbia University Libraries