Research Catalog

Title

Structural bioinformatics / edited by Philip E. Bourne, Helge Weissig.

Publication

New York : Wiley, [2003], ©2003.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• Bourne, Philip E.
• Weissig, Helge.

Description

xix, 649 pages : illustrations; 26 cm.

Summary

• "The emerging discipline of structural bioinformatics comprises the development of computational technologies for methods of storage, retrieval, and analysis of the three-dimensional structure of biological macromolecules. Edited by Philip Bourne and Helge Weissig, this groundbreaking text provides a thorough understanding of the theories, associated algorithms, resources, and tools used in structural bioinformatics.".
• "Readers will gain the ability to make effective use of protein, DNA, RNA, carbohydrate, and complex structures to better understand biological function. Molecular biologists, biochemists, biophysicists, and bioinformaticians in basic and clinical research, as well as undergraduate and graduate students in biology, medicine, and computer science, will find Structural Bioinformatics to be an essential addition to their professional and academic libraries."--BOOK JACKET.

Series Statement

Methods of biochemical analysis ; v. 44

Uniform Title

Methods of biochemical analysis ; v. 44.

Subjects

• Computational Biology
• Macromolecules > Structure > Computer simulation
• Bioinformatics
• Macromolecules > Structure > Mathematical models

Bibliography (note)

• Includes bibliographical references and index.

Contents

• Sect. I. Introduction -- 1. Defining Bioinformatics and Structural Bioinformatics / Russ B. Altman and Jonathan M. Dugan -- 2. Fundamentals of Protein Structure / Eric D. Scheeff and J. Lynn Fink -- 3. Fundamentals of DNA and RNA Structure / Stephen Neidle, Bohdan Schneider and Helen M. Berman -- 4. Computational Aspects of High-Throughput Crystallographic Macromolecular Structure Determination / Paul D. Adams, Ralf W. Grosse-Kunstleve and Axel T. Brunger -- 5. Macromolecular Structure Determination by NMR Spectroscopy / John L. Markley, Eldon L. Ulrich, William M. Westler and Brian F. Volkman -- 6. Electron Microscopy / Niels Volkmann and Dorit Hanein -- 7. Molecular Visualization / John Tate -- Sect. II. Data Representation and Databases -- 8. The PDB Format, mmCIF Formats, and Other Data Formats / John D. Westbrook and P. M. D. Fitzgerald -- 9. The Protein Data Bank / The PDB Team --
• 10. The Nucleic Acid Database / Helen M. Berman, John Westbrook, Zukang Feng, Lisa Iype, Bohdan Schneider and Christine Zardecki -- 11. Other Structure-Based Databases / Helge Weissig and Philip E. Bourne -- Sect. III. Comparative Features -- 12. Protein Structure Evolution and the Scop Database / Boojala V. B. Reddy and Philip E. Bourne -- 13. The Cath Domain Structure Database / C. A. Orengo, F. M. G. Pearl and J. M. Thornton -- 14. Structural Quality Assurance / Roman A. Laskowski -- 15. All-Atom Contacts: A New Approach to Structure Validation / Jane S. Richardson -- 16. Structure Comparison and Alignment / Philip E. Bourne and Ilya N. Shindyalov -- Sect. IV. Structure and Functional Assignment -- 17. Secondary Structure Assignment / Claus A. F. Andersen and Burkhard Rost -- 18. Identifying Structural Domains in Proteins / Lorenz Wernisch and Shoshana J. Wodak --
• 19. Inferring Protein Function from Structure / Gail J. Bartlett, Annabel E. Todd and Janet M. Thornton -- Sect. V. Protein Interactions -- 20. Prediction of Protein - Protein Interactions from Evolutionary Information / Alfonso Valencia and Florencio Pazos -- 21. Electrostatic Interactions / Nathan A. Baker and J. Andrew McCammon -- Sect. VI. Proteins as Drug Targets -- 22. Principles and Methods of Docking and Ligand Design / J. Krumrine, F. Raubacher, N. Brooijmans and I. Kuntz -- 23. Structural Bioinformatics in Drug Discovery / Eric B. Fauman, Andrew L. Hopkins and Colin R. Groom -- Sect. VII. Structure Prediction -- 24. CASP and CAFASP Experiments and their Findings / Philip E. Bourne -- 25. Homology Modeling / Elmar Krieger, Sander B. Nabuurs and Gert Vriend -- 26. Fold Recognition Methods / Adam Godzik -- 27. AB Initio Methods / Dylan Chivian, Timothy Robertson, Richard Bonneau and David Baker --
• 28. Prediction in 1D: Secondary Structure, Membrane Helices, and Accessibility / Burkhard Rost -- Sect. VIII. The Future -- 29. Structure Genomics / Stephen K. Burley and Jeffrey B. Bonanno.

ISBN

• 0471202002 (cloth : alk. paper)
• 0471201995

LCCN

2002011156

OCLC

• ocm50199108
• SCSB-4332827

Owning Institutions

Columbia University Libraries