Research Catalog

Title

Neurobiology of ischemic brain damage / edited by K. Kogure, K.-A. Hossmann, B.K. Siesjö.

Publication

Amsterdam ; New York : Elsevier, 1993.

Items in the Library & Off-site

Details

Additional Authors

• Hossmann, K.-A. (Konstantin-Alexander), 1937-
• Kogure, Kyuya.
• Sendai Symposium on Ischemic Brain Damage (2nd : 1992 : Okinawa-shi, Japan)
• Siesjö, Bo K.

Description

xiii, 283 p. : ill.; 27 cm.

Summary

In the eight years since the publication of Volume 63 of Progress in Brain Research, on this subject, developments in the research field have been very fast. For example, receptor physiology and pharmacology is now an intensively studied field, and the excitotoxic hypothesis of cell death is commonly accepted. Furthermore, it is recognized that ischemia and other insults give rise to a sustained depression of overall protein synthesis, yet lead to the expression of dormant genes and to synthesis of new proteins. In view of this development, this volume focusses on the cellular and molecular aspects of ischemic brain damage. The book will be of great value to all those interested in the pathophysiology of ischemic and traumatic brain damage.

Series Statement

Progress in brain research ; v. 96

Uniform Title

Progress in brain research ; v. 96.

Subjects

• Congress
• Brain Ischemia

Genre/Form

Congress.

Bibliography (note)

• Includes bibliographical references and index.

Contents

• 1. A new perspective on ischemic brain damage? / B. K. Siesjo -- 2. Temperature modulation of ischemic brain injury - a synthesis of recent advances / M. D. Ginsberg, M. Y.-T. Globus, W. D. Dietrich and R. Busto -- 3. Acidosis-related brain damage / B. K. Siesjo, K. Katsura, P. Mellergard, A. Ekholm, J. Lundgren and M.-L. Smith -- 4. Cerebral ischemia: the microcirculation as trigger and target / U. Dirnagl -- 5. Evaluation of the concomitance of lipid peroxidation in experimental models of cerebral ischemia and stroke / B. D. Watson -- 6. Role of superoxide dismutase in ischemic brain injury: reduction of edema and infarction in transgenic mice following focal cerebral ischemia / P. H. Chan, H. Kinouchi, C. J. Epstein, E. Carlson, S. F. Chen, S. Imaizumi and G. Y. Yang -- 7. Glutamate receptor transmission and ischemic nerve cell damage: evidence for involvement of excitotoxic mechanisms / N. H. Diemer, E. Valente, T. Bruhn, M. Berg, M. B. Jorgensen and F. F. Johansen.
• 8. Antagonism of the NMDA and non-NMDA receptors in global versus focal brain ischemia / W. Pulsinelli, A. Sarokin and A. Buchan -- 9. NMDA receptors and AMPA/kainate receptors mediate parallel injury in cerebral cortical cultures subjected to oxygen-glucose deprivation / D. W. Choi -- 10. Ischemia-induced disturbances of polyamine synthesis / W. Paschen, M. Cleef, G. Rohn, M. Muller and A. E. I. Pajunen -- 11. Disturbances of cerebral protein synthesis and ischemic cell death / K.-A. Hossmann -- 12. Protein phosphorylation and the regulation of mRNA translation following cerebral ischemia / T. Wieloch, K. Bergstedt and B. R. Hu -- 13. Stress protein and proto-oncogene expression as indicators of neuronal pathophysiology after ischemia / T. S. Nowak, Jr., O. C. Osborne and S. Suga -- 14. Possible involvement of c-fos translational regulation in the interaction between glutamate and neurotrophic factors in brain ischemia / K. Hisanaga and K. Kogure.
• 15. Selective gene expression after brain ischemia / K. Abe and K. Kogure -- 16. Molecular pathology of head trauma: altered [beta]APP metabolism and the aetiology of Alzheimer's disease / S. M. Gentleman, D. I. Graham and G. W. Roberts -- 17. Role of phospholipase A[subscript 2] and membrane-derived lipid second messengers in membrane function and transcriptional activation of genes: implications in cerebral ischemia and neuronal excitability / N. G. Bazan, G. Allan and E. B. Rodriguez de Turco -- 18. Presynaptic terminals in hippocampal gliosis following transient ischemia in the Mongolian gerbil / T. Kirino -- 19. Long-term structural and biochemical events in the hippocampus following transient global ischemia / H. Onodera, H. Aoki and K. Kogure.

ISBN

• 0444896031 (volume)
• 0444801049 (series)

Owning Institutions

Columbia University Libraries