Research Catalog

Title

Drug permeation enhancement : theory and applications / edited by Dean S. Hsieh.

Publication

New York : Dekker, c1994.

Items in the Library & Off-site

Details

Additional Authors

Hsieh, Dean, 1948-

Description

xi, 426 p. : ill.; 24 cm.

Series Statement

Drugs and the pharmaceutical sciences ; 62

Uniform Title

Drugs and the pharmaceutical sciences ; v. 62.

Subject

• Transdermal medication
• Skin > Permeability
• Nasal mucosa > Permeability
• Cornea > Permeability
• Dosage Forms
• Administration, Cutaneous
• Skin Absorption
• Administration, Intranasal

Bibliography (note)

• Includes bibliographical references and index.

Contents

• 1. Understanding Permeation Enhancement Technologies / Dean S. Hsieh -- 2. Skin Penetration Enhancers: Scientific Perspectives / Vinod P. Shah -- 3. Basic Mechanisms in Transepithelium Transport Enhancement / Wei-Chiang Shen and Yi-Jing Lin -- 4. Skin Permeation Enhancement Reversibility / Margo B. Haberkamp -- 5. Visualization of Drug Transport Across Human Skin and the Influence of Penetration Enhancers / H. E. Junginger, H. E. Bodde and F. H. N. de Haan -- 6. Compatibility and Synergy of Permeation Enhancers with Solvents, Excipients, and Drugs / Shirley M. Ng -- 7. A General Method for Assessing Skin Permeation Enhancement Mechanisms and Optimization / Charan R. Behl, Nancy J. Harper, Joyce Y. Pei, Saran Kumar, Deepak Mehta, Hing Char, Sunil B. Patel, David Piemontese, Giuseppe Ciccone and Waseem Malick -- 8. Permeation Enhancement with Ethanol: Mechanism of Action Through Skin / S. Yum, E. Lee, L. Taskovich and F. Theeuwes.
• 9. Liposomes as Penetration Promoters and Localizers of Topically Applied Drugs / Michael Mezei -- 10. Barrier Properties of the Skin: Skin Development and Permeation / Tamie Kurihara-Bergstrom and William R. Good -- 11. Iontophoresis: Fundamentals / Ooi Wong -- 12. Transdermal Delivery of Proteins and Peptides by Iontophoresis: Development, Challenges, and Opportunities / Jue-Chen Liu and Ying Sun -- 13. In Vivo Experience with Electrically Mediated Transdermal Drug Delivery / B. Robert Meyer -- 14. In Vivo and In Vitro Characteristics of Electro-Transdermal Drug Delivery / Mary Martin and John Devane -- 15. Transdermal Drug Delivery by Phonophoresis: Basics, Mechanisms, and Techniques of Application / Ying Sun and Jue-Chen Liu -- 16. Permeability and Metabolism as Barriers to Transmucosal Delivery of Peptides and Proteins / Bruce J. Aungst -- 17. Toxicological Evaluation of Intranasal Peptide and Protein Drugs / Michael A. Dorato.
• 18. Permeation Enhancement for Ocular Route of Polypeptide Administration / George C. Y. Chiou and Yu-Qun Zheng -- 19. Mechanisms of Ocular Peptide Absorption and Its Enhancement / Yongyut Rojanasakul.

ISBN

0824790154 (alk. paper)

LCCN

93009043

OCLC

• 28345930
• ocm28345930
• SCSB-4721668

Owning Institutions

Columbia University Libraries