Research Catalog

Anxiolytic [Beta]-carbolines : from molecular biology to the clinic

Title
Anxiolytic [Beta]-carbolines : from molecular biology to the clinic / editor, David N. Stephens.
Publication
Berlin ; New York : Springer-Verlag, c1993.

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Details

Additional Authors
Stephens, David N., 1946-
Description
x, 151 p. : ill.; 25 cm.
Series Statement
Psychopharmacology series ; v. 11
Uniform Title
Psychopharmacology series ; 11.
Subject
  • Abecarnil > Testing
  • Carbolines > Therapeutic use > Testing
  • GABA > Agonists > Therapeutic use > Testing
  • Tranquilizing drugs > Mechanism of action
  • Anti-Anxiety Agents
  • Carbolines > therapeutic use
  • gamma-Aminobutyric Acid > therapeutic use
  • Drug Antagonism
  • Drug Therapy
Bibliography (note)
  • Includes bibliographical references and index.
Contents
  • Discovery of [beta]-Carboline Ligands for Benzodiazepine Receptors / C. Braestrup and M. Nielsen -- [beta]-Carboline-3-Carboxylic Acid Ethyl Ester: A Lead for New Psychotropic Drugs / R. Schmiechen, D. Seidelmann and A. Huth -- Molecular Biology of Gamma-Aminobutyric Acid Type A/Benzodiazepine Receptors / H. Luddens -- Immunohistochemical Mapping of Gamma-Aminobutyric Acid Type A Receptor Alpha Subunits in Rat Central Nervous System / J. D. Turner, G. Bodewitz, C. L. Thompson and F. A. Stephenson -- Abecarnil is a Full Agonist at Some and a Partial Agonist at Other Recombinant Gamma-Aminobutyric Acid Type A Receptor Subtypes / I. Pribilla, R. Neuhaus, R. Huba, M. Hillmann, J. D. Turner, D. N. Stephens and H. H. Schneider -- Pharmacological Evidence for Full Agonist Activity of Abecarnil at Certain Receptors / M. Serra, C. A. Ghiani, C. Motzo and G. Biggio.
  • Abecarnil: A Novel Anxiolytic with Mixed Full Agonist/Partial Agonist Properties in Animal Models of Anxiety and Sedation / D. N. Stephens, L. Turski, G. H. Jones, K. G. Steppuhn and H. H. Schneider -- Abecarnil Shows Reduced Tolerance Development and Dependence Potential in Comparison to Diazepam / W. Loscher -- Behavioral Pharmacology of Abecarnil in Baboons: Reduced Dependence and Abuse Potential / C. A. Sannerud, N. A. Ator and R. R. Griffiths -- Abecarnil Used to Treat Benzodiazepine Withdrawal / M. W. Emmeti-Oglesby, D. A. Lytle and S. A. English -- Abecarnil, A New [beta]-Carboline Anxiolytic: Preliminary Clinical Pharmacology / T. Duka, W. Krause, R. Dorow, A. Rohloff, H. Ott and B. Voet.
ISBN
  • 3540571442 (Berlin)
  • 0387571442 (New York)
LCCN
93033447
OCLC
  • 28966403
  • ocm28966403
  • SCSB-4722279
Owning Institutions
Columbia University Libraries