Research Catalog

Title

The Tachykinin receptors / edited by Stephen H. Buck.

Publication

Totowa, N.J. : Humana Press, [1994], ©1994.

Items in the Library & Off-site

Holdings

Details

Additional Authors

Buck, Stephen H.

Description

xi, 630 pages : illustrations; 24 cm.

Summary

• The Tachykinin Receptors constitutes the first complete survey and synthesis of the field, and thus is now clearly the standard resource for all those conducting research on this centrally important class of receptors today.
• The Tachykinin Receptors offers a state-of-the-art review by international experts on all aspects of tachykinin receptors, including neuropeptide/peptide and G-protein-linked receptors in general. It covers the physiology, pharmacology, biochemistry, and molecular biology of these receptors from both clinical and basic research points of view.
• The tachykinin are currently one of the most intensively studied peptide families and the first neuropeptide family for which a receptor structure was elucidated. Topics treated by the distinguished contributors include the characterization of tachykinin receptors, the mechanisms of tachykinin receptor action, a reflection on future prospects, and a historical consideration of tachykinin research.

Series Statement

Receptors

Uniform Title

Receptors.

Subject

• Receptors, Tachykinin
• Tachykinins > Receptors

Note

• Includes bibliographical references and index.

Contents

• 1. History of Tachykinin Peptides / John E. Maggio and Patrick W. Mantyh -- 2. History of Tachykinin Receptors / Leslie L. Iversen -- 3. Biochemical Methods and Assays / Paul L. M. van Giersbergen and Stephen H. Buck -- 4. Agonist and Antagonist Receptor Binding / Stafford McLean and John A. Lowe III -- 5. Comparative Distribution of Receptor Types in the Mammalian Brain / Than-Vinh Dam and Remi Quirion -- 6. Autoradiographic Localization of Receptors in Peripheral Tissues / Elizabeth Burcher, Christian J. Mussap and Jennifer A. Stephenson -- 7. Molecular Biology of Receptors: Structures, Expression, and Regulatory Mechanisms / James E. Krause, Paul Blount and Bruce S. Sachais -- 8. Characterization of the NK[subscript 1] Receptor Using Photoaffinity Probes / Norman D. Boyd, Reinhard K. Kage and Susan E. Leeman -- 9. Modeling of G-Protein-Coupled Receptors: Application to the NK[subscript 1] Tachykinin Receptor / Susanne Trumpp-Kallmeyer, Jan Hoflack and Marcel Hibert.
• 10. Receptors and the Inositol Phosphate-Calcium Signaling System / James W. Putney, Jr. -- 11. Signal Transduction Mechanisms of Tachykinin Effects on Ion Channels / Yasuko Nakajima and Shigehiro Nakajima -- 12. Structure-Activity Relationships of Agonist and Antagonist Ligands / Scott L. Harbeson and Paolo Rovero -- 13. Pharmacological Characterization of Receptor Types / Domenico Regoli, Noureddine Rouissi and Pedro D'Orleans-Juste -- 14. Evidence for Receptor Subtypes/Species Variants of Receptors / Carlo Alberto Maggi -- 15. Role of Receptors in Nociception / Raymond G. Hill -- 16. Pharmacological Characterization of Receptors in the Spinal Cord of the Newborn Rat / Masanori Otsuka, Hidenori Suzuki, Mitsuhiko Yanagisawa, Rumiko Hosoki, Jian-Zhong Guo and Koichi Yoshioka -- 17. Receptor Function in the Periphery / Judith M. Hall -- 18. Receptor Involvement in Pathology and Disease / Patrick W. Mantyh, Steven R. Vigna and John E. Maggio.
• 19. Summary, Thoughts, and Future Perspectives / Fred Lembeck and Stephen H. Buck.

ISBN

0896032663

LCCN

94013436

Owning Institutions

Columbia University Libraries