Research Catalog

Title

Neurobehavioral toxicity : analysis and interpretation / editors, Bernard Weiss, John L. O'Donoghue.

Publication

New York : Raven Press, c1994.

Items in the Library & Off-site

Details

Additional Authors

• O'Donoghue, John L.
• Weiss, Bernard.

Description

xix, 391 p. : ill.; 24 cm.

Subjects

• Congress
• Behavioral toxicology > Congresses
• Toxicology
• Nervous System
• Neurotoxins

Genre/Form

Congress.

Note

• Papers presented at the proceedings of the workshop held in 1992.

Bibliography (note)

• Includes bibliographical references and index.

Contents

• Robert Infurna: A Perspective / Elissa Savrin -- 1. Introduction / W. Kent Anger -- 2. Behavioral Analysis in Neurotoxicology / Robert C. MacPhail -- 3. Defining What Is Neurotoxic / John L. O'Donoghue -- 4. Criteria for Determining Neurotoxic Potential: Identification and Reportability Under the Toxic Substances Control Act / Suzanne B. McMaster -- 5. A Neurotoxicologic Definition of Adverse / Joel L. Mattsson -- 6. Criteria for Determining Neurotoxic Potential / Wayne C. Daughtrey -- 7. Discussion Summary / Wayne C. Daughtrey -- 8. Issues in Developmental Toxicology / Linda Patia Spear -- 9. Neurobehavioral Evaluations: Integral Components of Developmental Toxicity Testing / Patrick J. Wier -- 10. Neurotoxicity Testing Standards: A Contract Pathologist's Perspective / Robert H. Garman -- 11. Statistical Issues for Animal Studies of Developmental Neurotoxicity / Christopher Cox -- 12. Introduction / Jurg Elsner -- 13. Neurotoxicity Expressed in Naturally Occurring Behavior / Hugh L. Evans.
• 14. The Application of a Functional Observational Battery and Motor Activity Test in Safety Assessment Studies / John A. Foss -- 15. Utility of Activity and Observational Data for Neurotoxicity Screening / Virginia C. Moser -- 16. Are Present-Day Behavioral Observations Valid Indicators of Neurotoxicity? / Brian R. Broxup, Peter C. Beyrouty and Keith J. Robinson -- 17. A Graphic Model for Discussing Activity and Observational Data / John L. Orr -- 18. The Role of Motor Activity in the Assessment of Neurotoxicity / Mark E. Stanton -- 19. Schedule-Controlled Operant Behavior: Critical Summary of Workshop Discussion and Implications / D. Cooper Rees and Abby A. Li -- 20. Implications of Changes in Schedule-Controlled Operant Behavior / Deborah A. Cory-Slechta -- 21. The Use of Schedule-Controlled Behavior in Toxicity Testing / Galen R. Wenger.
• 22. Toxicologic Interpretation of Neurobehavioral Data: Does Schedule-Controlled Operant Behavior Testing Have a Role in Regulatory Toxicology? / Thomas H. Gardiner -- 23. The Role of Schedule-Controlled Operant Behavior in the Identification of Toxic Effects of Environmental Chemicals / William F. Sette -- 24. The Use (Misuse) of Schedule-Controlled Operant Behavior in Neurotoxicity Testing / Abby A. Li -- 25. Schedule-Controlled Operant Behavior During the Hazard Identification Stage of Neurotoxicity Risk Assessment / Victor G. Laties -- 26. Introduction / Steven G. Gilbert -- 27. Operant Behavior and the Measurement of Motor Dysfunction / M. Christopher Newland -- 28. Testing Effects of Toxicants on Sensory System Function by Operant Methodology / Deborah C. Rice -- 29. Using the Development of Fixed-Ratio Schedule Control to Detect Long-Term Effects of Drugs and Toxicants / G. David Gentry and Lawrence D. Middaugh.
• 30. Analysis of Brain Function Using a Battery of Schedule-Controlled Operant Behaviors / Merle G. Paule -- 31. Operant Methodology: An Evaluation in the Context of the Multi-Substance Rule for Solvent Neurotoxicity Testing / Jacques P. J. Maurissen -- 32. Interpretation of Neurobehavioral Data in Toxicologic Studies / Hugh A. Tilson and Robert C. MacPhail -- 33. Case Studies in Industrial Neurotoxicology / Michael W. Gill -- 34. Toluene: A Prototype for the Evaluation of the Behavioral and Nervous System Toxicity of Solvents / Ronald W. Wood -- 35. The Coming Agenda for Neurobehavioral Toxicology / Bernard Weiss.

ISBN

0781701724

LCCN

93048577

Owning Institutions

Columbia University Libraries