Research Catalog

Title

Nasal toxicity and dosimetry of inhaled xenibiotics : implications for human health / cosponsors, Chemical Industry Institute of Toxicology ... [et al.] ; organizing committee, chairman, F. Miller ; G. Boorman ... [et al.].

Publication

Washington, D.C. : Taylor & Francis, c1995.

Items in the Library & Off-site

Details

Additional Authors

• Boorman, Gary A.
• Chemical Industry Institute of Toxicology.
• Miller, Fred J.

Description

x, 469 p. : ill.; 26 cm.

Uniform Title

Inhalation toxicology. V. 6 (Supplement)

Subjects

• Xenobiotics
• Nose > Effect of chemicals on > Congresses
• Gas Poisoning
• Congress
• Gases, Asphyxiating and poisonous > Toxicology > Congresses
• Nasal Cavity > physiopathology
• Gases, Asphyxiating and poisonous > Toxicology > Dose-response relationship > Congresses
• Environmental Exposure > adverse effects

Genre/Form

Congress.

Note

• "Inhalation toxicology, volume 6, supplement"--Table of contents p. [v]-vii.

Bibliography (note)

• Includes bibliographical references and index.

Contents

• Preface / Frederick J. Miller -- Our Upper Airways and Our Ambient Air: A Historical Perspective / Donald F. Proctor -- Research Strategy for Assessing Human Risk from Inhaled Nasal Toxicants / Roger O. McClellan -- Nasal Toxicity: End Points of Concern in Humans / Donald A. Leopold -- Nasal Dosimetry, Lesion Distribution, and the Toxicologic Pathologist: A Brief Review / Kevin T. Morgan -- Dosimetry Modeling: Approaches and Issues / James S. Ultman -- Issues in Modeling Dosimetry in Rats and Primates / J. S. Kimbell -- Nasal Dosimetry Modeling for Humans / Peter W. Scherer, Keyvan Keyhani and Maxwell M. Mozell -- In Vivo Measurements of Uptake / John B. Morris -- Modeling the Uptake of Gases by the Dog Nasal-Pharyngeal Region: Effects of Morphometric and Physicochemical Factors / John H. Overton and Richard C. Graham -- Ozone Dosimetry Studies in the Nose and Eye Using Oxygen-18 / Gary E. Hatch, Jack R. Harkema, Charles G. Plopper and Linda Harris.
• Comparison of Four Biologically Based Dosimetry Models for the Deposition of Rapidly Metabolized Vapors in the Rodent Nasal Cavity / Clay B. Frederick, John B. Morris, Julia S. Kimbell, Kevin T. Morgan and Peter W. Scherer -- Nasal Dosimetry of Formaldehyde: Modeling Site Specificity and the Effects of Preexposure / Henry d'A. Heck and Mercedes Casanova -- Nasal Lesion Distribution and Toxicity in the Squamous Epithelial Region / Thomas M. Monticello and Kevin T. Morgan -- Ozone-Induced Proliferative and Metaplastic Lesions in Nasal Transitional and Respiratory Epithelium: Comparative Pathology / Jack R. Harkema and Jon A. Hotchkiss -- Olfactory Mucosal Toxicity. Integration of Morphological and Biochemical Data in Mechanistic Studies: Dibasic Esters as an Example / Matthew S. Bogdanffy and Steven R. Frame -- Accessory Nasal Structures in Toxicology Studies / Robert C. Sills, Kevin T. Morgan and Gary A. Boorman.
• Human Olfactory Epithelium: Normal Patterns and Types of Lesions Found in the General Population / Barbara R. Talamo, Wen-Hui Feng and Margo Stockmayer -- Toxicity of Nasal Respiratory Mucosa in Humans / Valerie J. Lund -- Threshold Limit Values: How They are Established and Their Role in the Workplace / John Doull -- Management of Occupational Exposure Levels in the United States / Richard W. Niemeier -- Inhalation RfC Methodology: Dosimetric Adjustments and Dose-Response Estimation of Noncancer Toxicity in the Upper Respiratory Tract / Annie M. Jarabek -- U.S. EPA Inhalation Reference Concentration for Bromomethane / Daniel J. Guth and Annie M. Jarabek -- Evaluation of Nasal Tract Lesions in Derivation of the Inhalation Reference Concentration for Hexamethylene Diisocyanate / Gary L. Foureman, Mark M. Greenberg, Ghona K. Sangha, Barry P. Stuart, Ronald N. Shiotsuka and Juergen H. Thyssen.

ISBN

1560323663 (cloth) :

LCCN

94029943

Owning Institutions

Columbia University Libraries