Research Catalog
The case of the frozen addicts / J. William Langston and Jon Palfreman.
- Title
- The case of the frozen addicts / J. William Langston and Jon Palfreman.
- Author
- Langston, J. W. (James William)
- Publication
- New York : Pantheon Books, [1995], ©1995.
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Status | Format | Access | Call Number | Item Location |
---|---|---|---|---|
Text | Request in advance | RC382 .L37 1995 | Off-site |
Holdings
Details
- Additional Authors
- Palfreman, Jon.
- Description
- ix, 309 pages : illustrations; 24 cm
- Summary
- As scientists raced to capitalize on this breakthrough, Dr. Langston struggled to salvage the lives of his frozen patients, for whom L-dopa provided only short-term relief. The solution he found lay in the most daring area of research: fetal-tissue transplants.
- Dr. Langston determined that this patient and five others had all used the same tainted batch of synthetic heroin, inadvertently laced with a toxin that had destroyed an area of their brains essential to normal movement. This same area, the substantia nigra, slowly deteriorates in Parkinson's disease.
- In the summer of 1982, hospital emergency rooms in the San Francisco Bay Area were suddenly confronted with mysteriously "frozen" patients - young men and women who, though conscious, could neither move nor speak. Doctors were baffled, until neurologist J. William Langston, recognizing the symptoms of advanced Parkinson's disease, administered L-dopa - the only known effective treatment - and "unfroze" his patient.
- The astonishing recovery of two of his patients garnered worldwide press coverage, helped overturn federal restrictions on fetal-tissue research, and offered hope to millions suffering from Parkinson's, Alzheimer's, and other degenerative brain disorders.
- Subjects
- Substantia Nigra > transplantation
- Substantia Nigra > embryology
- Fetal tissues > Transplantation > Case studies
- Case Reports
- Designer drugs > Toxicology
- Fetal Tissue Transplantation
- Brain Tissue Transplantation
- Methylphenyltetrahydropyridine > Physiological effect
- Parkinson's disease > Animal models
- Parkinson's disease > Case studies
- Parkinson Disease > therapy
- Genre/Form
- Case Reports.
- Note
- Includes index.
- ISBN
- 0679424652
- LCCN
- 94043202
- Owning Institutions
- Columbia University Libraries