Research Catalog

Analysis of free radicals in biological systems / edited by A. E. Favier ... [et al.].

Title
Analysis of free radicals in biological systems / edited by A. E. Favier ... [et al.].
Publication
Basel ; Boston : Birkhäuser Verlag, c1995.

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Book/TextUse in library RB170 .A53 1995Off-site

Details

Additional Authors
Favier, Alain, 1945-
Description
x, 312 p. : ill.; 24 cm.
Summary
  • The main aim of the book is to provide a comprehensive survey on recent methodological aspects of the measurement of damage within cellular targets, information which may be used as an indicator of oxidative stress.
  • In the introductory chapters, emphasis is placed on the chemical properties of reactive oxygen species and their role in the induction of cellular modifications together with their links to various diseases. The central part of the book is devoted to the description of selected methods aimed at monitoring the production of free radicals in cellular systems.
  • In addition, several assays are provided to assess the chemical damage induced by reactive oxygen species in critical cellular-targets in vitro and in humans in vivo.
  • Thus both practical aspects and general considerations, including discussions on the applications and limitations of the assays, are critically reviewed. One of the major features of the book is the description of new experimental methods. These include the measurement of oxydized DNA bases and nucleosides, new techniques for the determination of LDL oxidation using spin-trap agents, and the use of salicylate as an indicator of oxidative stress.
  • In addition, more classical though significantly improved techniques devoted to the measurement of hydroperoxides and aldehydes are described. The book will serve a large scientific community including biologists, chemists, and clinicians working on the chemical and biological effects of oxidative stress. It may also be of interest to investigators in the fields of drug, cosmetic and new food research.
Subjects
Bibliography (note)
  • Includes bibliographical references and index.
Contents
  • Chemistry of dioxygen and its activated species / J.-L. Pierre -- Biological sources of reduced oxygen species / V. Niviere and M. Fontecave -- Nitric oxide: Chemistry and biology / C. Garrel and M. Fontecave -- Pro-oxidant and antioxidant effects of nitric oxide / N. Hogg -- Oxidative damage to DNA / J. Cadet, M. Berger, B. Morin, S. Raoul and J. R. Wagner -- Oxidation of low density lipoprotein (LDL) by cells / S. Parthasarathy -- Free radicals and antioxidants in human diseases / J. Pincemail -- How to demonstrate the occurrence of an oxidative stress in human? / A. E. Favier -- EPR evidence of generation of superoxide anion radicals [actual symbol not reproducible] by irradiation of a PDT photosensitizer: Hypericin / C. Hadjur and A. Jeunet -- Nitrone spin traps as reagents for the study of oxidative modification of low density lipoproteins: Implications for atherosclerosis / C. E. Thomas --
  • Ascorbate radical: A valuable marker of oxidative stress / G. R. Buettner and B. A. Jurkiewicz -- Lipid hydroperoxide analysis by reverse-phase high-performance liquid chromatography with mercury cathode electrochemical detection / W. Korytowski and A. W. Girotti -- Determination of primary and secondary lipid peroxidation products: Plasma lipid hydroperoxides and thiobarbituric acid reactive substances / C. Coudray, M. J. Richard and A. E. Favier -- Measurement of low-density lipoprotein oxidation / I. Hininger, A. David, F. Laporte, A.-M. Roussel, T. Foulon, P. Groslambert and A. Hadjian -- Determination of 8-oxo-purines in DNA by HPLC using amperometric detection / T. Douki, M. Berger, S. Raoul, J.-L. Ravanat and J. Cadet -- Measurement of one of the features of apoptosis: DNA fragmentation / J. Mathieu, S. Ferlat, D. Ferrand, S. Platel, B. Ballester, J. C. Mestries, Y. Chancerelle and J. F. Kergonou --
  • Measurement of plasma sulfhydryl and carbonyl groups as a possible indicator of protein oxidation / P. Faure and J.-L. Lafond -- Measurement of oxidized nucleobases and nucleosides in human urine by using a GC/MS assay in the selective ion monitoring mode / M.-F. Incardona, F. Bianchini, A. E. Favier and J. Cadet -- Methodological and practical aspects for in vitro studies of oxidative stress on cell culture model (toxicity and protection) / M. J. Richard and P. Guiraud -- Detection and production of nitric oxide / C. Garrel, J.-L. Decout and M. Fontecave -- Salicylate hydroxylation products assay as a marker of oxidative stress in man: A sensitive HPLC-electrochemical method / C. Coudray, M. Talla, S. Martin, M. Fatome and A. E. Favier.
ISBN
  • 3764351373 (Basel : acid-free paper)
  • 0817651373 (Boston)
LCCN
95021845
OCLC
  • 32698922
  • ocm32698922
  • SCSB-4780664
Owning Institutions
Columbia University Libraries