Research Catalog

Title

Multidrug resistance in cancer cells : molecular, biochemical, physiological, and biological aspects / edited by Sudhir Gupta and Takashi Tsuruo.

Publication

Chichester ; New York : Wiley, c1996.

Items in the Library & Off-site

Details

Additional Authors

• Gupta, Sudhir
• Tsuruo, Takashi

Description

xii, 507 p. : ill.; 26 cm.

Subjects

• Multidrug resistance
• Drug resistance in cancer cells
• Carrier Proteins > physiology
• Drug Resistance, Neoplasm
• Drug Resistance, Multiple > physiology
• Tumor Cells, Cultured

Bibliography (note)

• Includes bibliographical references and index.

Contents

• 1. Cloning and Structure: Function Analysis of the Mouse mdr Gene Family / Maya Hanna and Philippe Gros -- 2. Functional and Molecular Characterization of the Human Multidrug Transporter / Christine A. Hrycyna, Shudong Zhang, Muralidhara Ramachandra, Baofu Ni, Ira Pastan and Michael M. Gottesman -- 3. Regulation of MDR Genes / Marilyn M. Cornwell -- 4. Cytogenetic Manifestations of Multidrug Resistance / June L. Biedler and Barbara A. Spengler -- 5. Chromosomal and Extrachromosomal Localization of Human MDR Genes / Patricia V. Schoenlein -- 6. MRP, Mode of Action and Role in MDR / Guido J. R. Zaman and Piet Borst -- 7. Role of LRP/Major Vault Protein in Multidrug Resistance / Rik J. S. Scheper, George L. Scheffer, Marcel J. Flens, Paul van der Valk, Chris J. L. M. Meijer, Herbert M. Pinedo, Hans C. Clevers, Marilyn L. Slovak, Leonard H. Rome, Robert H. Shoemaker and Miguel A. Izquierdo --
• 8. DNA Topoisomerase I Inhibitors and Multidrug Resistance / Yves Pommier, Akira Fujimori, Yuko Hoki, Malini Gupta and Marzia Gariboldi -- 9. The Role of Topoisomerase II in Multidrug Resistance / Shigeru Yamada and Koichi Ando -- 10. Glutathione and Glutathione-associated Enzymes in Multidrug Resistance / Linda R. Barone and Kenneth D. Tew -- 11. Oncogenes and Tumor Suppressor Genes in Multidrug Resistance / Tatyana N. Ignatova and William T. Beck -- 12. Drug Sensitivity Genes: Identification and Analysis Using the Genetic Suppressor Element Approach / Andrei V. Gudkov -- 13. Changes in Membrane Ionic Conductances Associated with Multidrug Resistance / Keisuke Kouyama, Anthony C. Chao and Phyllis Gardner -- 14. Identification and Characterization of the Drug-binding Sites of P-glycoprotein / Ahmad R. Safa -- 15. Phosphorylation of Proteins Involved in Multidrug Resistance / Timothy C. Chambers -- 16. Protein Kinase C and its Isozymes in Multidrug Resistance / Sudhir Gupta --
• 17. Non-PKC Kinases and Multidrug Resistance / Irene Abraham -- 18. P-glycoprotein Expression in Normal Human Tissues / James P. O'Brien and Carlos Cordon-Cardo -- 19. P-glycoprotein in the Normal Hematopoietic Progenitors and Cells of the Immune System / Sudhir Gupta -- 20. Role of P-glycoprotein in the Transport of Hormones and Peptides / Kazumitsu Ueda, Kouichi Kino, Yoshitomo Taguchi, Kouji Yamada, Tohru Saeki, Yusuke Tanigawara and Tohru Komano -- 21. Role of P-glycoprotein in the Blood-Brain Barrier / Mikihiko Naito and Takashi Tsuruo -- 22. Transport of P-glycoprotein-modifying Agents by P-glycoprotein / Keisuke Yusa, Mikihiko Naito and Takashi Tsuruo -- 23. Mice with Disrupted P-glycoprotein Genes / Piet Borst and A. H. Schinkel -- 24. Molecular Pharmacology of Reversal of Multidrug Resistance and its Clinical Implications / Ellen Friche and William T. Beck -- 25. Multidrug Resistance-reversing Agents for Potential Clinical Use / Osamu Nakanishi and Takashi Tsuruo --
• 26. Cyclosporins and Related Fungal Products in the Reversal of P-glycoprotein-mediated Multidrug Resistance / Francis Loor -- 27. Oligonucleotide Modulation of Multidrug Resistance Gene Expression / Tsukasa Ohkawa, Hiroshi Kijima, Akira Irie, George Horng, Anna Kaminski, Jerry Tsai, Brandon I. Kashfian and Kevin J. Scanlon -- 28. Application of the MDR1 Gene for Human Gene Therapy / Yoshizaku Sugimoto, Takashi Tsuruo, Ira Pastan and Michael M. Gottesman -- 29. Reversal of MDR in Acute Leukemia and Non-Hodgkin's Lymphoma / William S. Dalton -- 30. Prognostic Significance and Reversal of MDR in Multiple Myeloma / Pieter Sonneveld -- 31. Reversal of MDR in Solid Tumors / Giuseppe Giaccone and Herbert M. Pinedo.

ISBN

0471967122 (hbk : alk. paper)

LCCN

96013797

OCLC

• 34473173
• ocm34473173
• SCSB-4781649

Owning Institutions

Columbia University Libraries