Research Catalog

Title

Gene transfer in the cardiovascular system / edited by Keith L. March.

Publication

Boston : Kluwer Academic Publishers, c1997.

Items in the Library & Off-site

Details

Additional Authors

March, Keith Leonard, 1963-

Description

xvii, 516 p. : ill.; 25 cm.

Series Statement

Developments in cardiovascular medicine ; v. 189

Uniform Title

Developments in cardiovascular medicine ; v. 189.

Subject

• Cardiovascular system > Diseases > Gene therapy
• Gene Transfer Techniques
• Genes, Viral
• Cardiovascular Diseases > therapy
• Genetic Therapy
• Genetic Vectors

Note

• Includes index.

Contents

• Preface: Molecular and Mechanical Aspects of Gene Transfer / Keith L. March -- Vectors and Gene Transfer Systems: Molecular Aspects of Delivery. 1. Development of Viral Vectors for Human Gene Therapy: Retrovirus and Adenovirus (Part I) / Bruce C. Trapnell and Michael N. Pensiero. 2. Adenoviruses (Part II): Improvement of Adenoviral Vectors for Human Gene Therapy: E1 and E4 Deleted Recombinant Adenoviruses / J. F. Dedieu, E. Vigne and C. Orsini [et al.]. 3. Adeno-associated Virus and Other New DNA Virus Vectors / Terence R. Flotte, Sandra A. Afione and Barry J. Byrne. 4. Plasmid and Other Non-Viral Vectors / Linda B. Jacobsen. 5. The HVJ/Liposome Molecular Delivery System for In Vivo Genetic Engineering / Gary H. Gibbons. 6. Endogenous Expression Modification: Antisense Approaches / Michael Simons -- Methods for Localizing Gene Transfer: Mechanical Aspects of Delivery. 7. Catheter-Based Local Drug and Gene Delivery / Robert L. Wilensky.
• 8. Fluid Dynamics of Catheter Delivery: Effects on Delivery Efficiency and Localization / Charles R. Lambert and Stephen Rowland. 9. Targeted and Sustained-Release Delivery Concepts in Gene Therapy / Robert W. Schroff and Lawrence L. Kunz -- Gene Delivery for Local Vascular Expression. 10. Viral Vector-Based Vascular Gene Delivery: Basic Studies and Therapeutic Applications / Elizabeth G. Nabel. 11. Cell-Based Vascular Gene Delivery: Endothelial Cells as Carriers / James Burke, John Ojeifo and James A. Zwiebel. 12. Cell-Based Gene Delivery: Smooth Muscle Cells as Carriers / Alexander W. Clowes. 13. Vascular Cell Proliferation Dynamics: Implications for Gene Transfer and Restenosis / Robert S. Schwartz, Aloysius Chu and Myung Ho Jeong [et al.]. 14. Angiogenesis and Collateral formation / Jeffrey M. Isner -- Gene Delivery for Local Cardiac Expression. 15. Cell-Based Myocardial Protein Delivery / Mark H. Soonpaa and Loren J. Field.
• 16. Skeletal Myoblast Therapy in Cardiovascular Disease / Doris A. Taylor, Brian H. Annex and William E. Kraus [et al.]. 17. Adenovirus and the Myocardium / Jeffrey A. Towbin -- Gene Delivery for Systemic Expression. 18. Gene Delivery for Systemic Expression: Plasmid, Retroviral, and Adenoviral Approaches / Katherine Parker Ponder. 19. Adenoviral Gene Delivery Approaches for Systemic Expression / Susan C. Stevenson and Alan McClelland. 20. Experimental Approaches Using Kallikrein Gene Therapy for Hypertension / Julie Chao and Lee Chao -- Biophysical Considerations in Vector Delivery. 21. Pharmacokinetics of Local Vector Delivery To Vascular Tissues: Implications for Efficiency and Localization / Keith L. March and Bruce Trapnell.

ISBN

0792398599 (alk. paper)

LCCN

96029740

OCLC

• 501485037
• ocn501485037
• SCSB-4782781

Owning Institutions

Columbia University Libraries