Research Catalog

Title

The nature and origin of amyloid fibrils / [editors, Gregory R. Bock (Organizer) and Jamie A. Goode].

Publication

Chichester ; New York : Wiley, 1996.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• Bocke, Gregory.
• Goode, Jamie.

Description

xi, 253 pages : illustrations; 24 cm.

Series Statement

Ciba Foundation symposium ; 199

Uniform Title

Ciba Foundation symposium ; 199.

Subjects

• Congress
• Amyloid beta-protein > Congresses
• Amyloidosis > Congresses
• Amyloid beta-Peptides
• Amyloid > Congresses

Genre/Form

Congress.

Note

• "Symposium on The nature and origin of amyloid fibrils, held at the Palácio dos Marqueses de Pombal, Oeiras, Portugal, 23-25 October 1995"--Contents.

Bibliography (note)

• Includes bibliographical references and indexes.

Contents

• Chairman's introduction / P. P. Costa -- A molecular model of the amyloid fibril / C. C. F. Blake, L. C. Serpell, M. Sunde, O. Sandgren and E. Lundgren -- Refined fibril structures: the hydrophobic core in Alzheimer's amyloid [beta]-protein and prion as revealed by X-ray diffraction / H. Inouye and D. A. Kirschner -- General discussion I: Fibril structure -- General discussion I: Amyloid fibril toxicity -- Modulating conformational factors in transthyretin amyloid / M. J. M. Saraiva, M. R. Almeida, I. L. Alves, M. J. Bonifacio, A. M. Damas, J. A. Palha, G. Goldsteins and E. Lundgren -- Proteoglycans and amyloid fibrillogenesis / R. Kisilevsky and P. Fraser --
• Molecular mechanisms of fibrillogenesis and the protective role of amyloid P component: two possible avenues for therapy / M. B. Pepys, G. A. Tennent, D. R. Booth, V. Bellotti, L. B. Lovat, S. Y. Tan, M. R. Persey, W. L. Hutchinson, S. E. Booth, S. Madhoo, A. K. Soutar, P. N. Hawkins, R. Van Zyl-Smit, J. M. Campistol, P. E. Fraser, S. E. Radford, C. V. Robinson, M. Sunde, L. C. Serpell and C. C. F. Blake -- General discussion II: Human calcitonin fibrillogenesis -- General discussion II: Proteolysis of amyloidogenic proteins -- Metabolism of amyloid proteins / M. D. Benson, B. Kluve-Beckerman, J. J. Liepnieks, J. R. Murrell, D. Hanes and T. Uemichi -- Alzheimer's disease: genesis of amyloid / K. Beyreuther, G. Multhaup and C. L. Masters -- Apolipoprotein E and amyloidogenesis / B. Frangione, E. M. Castano, T. Wisniewski, J. Ghiso, F. Prelli and R. Vidal --
• Interaction of transthyretin with amyloid [beta]-protein: binding and inhibition of amyloid formation / A. L. Schwarzman and D. Goldgaber -- General discussion III: Apolipoprotein E, TTR and Alzheimer's disease -- [beta]-amyloid precursor protein and early-onset Alzheimer's disease / L. Hendriks, C. De Jonghe, P. Cras, J.-J. Martin and C. Van Broeckhoven -- Prion protein amyloid: separation of scrapie infectivity from PrP polymers / H. Wille, M. A. Baldwin, F. E. Cohen, S. J. DeArmond and S. B. Prusiner -- General discussion IV: Cell free conversion of protease-sensitive prion protein to the protease-resistant state: requirement for aggregates of scrapie-associated prion protein -- Ageing and amyloid fibrillogenesis: lessons from apolipoprotein AI, transthyretin and islet amyloid polypeptide / P. Westermark, K. Sletten and K. H. Johnson -- General discussion V: 4'-lodo-4'-deoxydoxorubicin for the treatment of AL amyloidosis --
• FAP mutations destabilize transthyretin facilitating conformational changes required for amyloid formation / W. Colon, Z. Lai, S. L. McCutchen, G. J. Miroy, C. Strang and J. W. Kelly.

ISBN

0471963615 (alk. paper)

LCCN

96002872

Owning Institutions

Columbia University Libraries