Research Catalog

Title

Sense and senility : the neuropathology of the aged human brain / David M.A. Mann.

Author

Mann, David M. A.

Publication

Austin : R.G. Landes Co., 1997.

Items in the Library & Off-site

Holdings

Details

Description

198 pages : illustrations; 26 cm.

Series Statement

Neuroscience intelligence unit

Uniform Title

Neuroscience intelligence unit.

Subjects

• Brain > physiology
• Nerve Degeneration > physiology
• Nervous system > Degeneration
• Nervous system > Aging
• Aging > physiology
• Alzheimer Disease > physiopathology

Bibliography (note)

• Includes bibliographical references and index.

Contents

• 1. Introduction -- 2. Pathological Changes in the Elderly Human Brain. 2.0. Introduction. 2.1. Gross Changes in the Brain. 2.2. Nerve Cell Numbers in Aging. 2.3. Regressive Changes in Neurones with Aging. 2.4. Senile Plaques. 2.5. Neurofibrillary Tangles. 2.6. Lewy Bodies. 2.7. Hirano Bodies. 2.8. Granulovacuolar Degeneration. 2.9. Neuropigments. 2.10. Other Neuronal Changes. 2.11. Changes in Glial Cells. 2.12. Cerebrovascular Changes. 2.13. Brain Aging: Compensation Versus Redundancy -- 3. Pathological Changes in Neurodegenerative Disease. 3.1. Introduction. 3.2. The Pathological Changes of Alzheimer's Disease. 3.3. The Initial Site of Damage. 3.4. The Presence of Alzheimer-type Pathology in Situations Other than AD. 3.5. The Pathogenesis of Alzheimer's Disease. 3.6. Systemic Changes in AD. 3.7. The Pathological Changes of Parkinson's Disease -- 4. Etiological Considerations. 4.1. Genetic Factors. 4.2. Environmental Factors --
• 5. Relationships Between Aging and Neurodegenerative Disease. 5.0. Introduction. 5.1. Pathology in the Normal Elderly-Preclinical Disease? 5.2. Implications for Aging Research. 5.3. The Concept Normality. 5.4. Relevance of Animal Studies. 5.5. Aging and Disease - A Continuum. 5.6. Genetic Susceptibility. 5.7. Concluding Remarks.

ISBN

0412134314 (alk. paper)

LCCN

96029707

Owning Institutions

Columbia University Libraries