Research Catalog

Title

Gene therapy for diseases of the lung / edited by Kenneth L. Brigham.

Publication

New York : M. Dekker, c1997.

Items in the Library & Off-site

Details

Additional Authors

Brigham, Kenneth L.

Description

xviii, 427 p. : ill.; 24 cm.

Summary

• This up-to-the-minute and comprehensive resource lucidly covers gene therapy for lung diseases from existing technologies delivering foreign DNA to the lungs via the airways or circulation to promising new approaches for the further development of safe and efficient gene delivery systems.
• Containing over 1350 bibliographic citations, tables, drawings, and photographs, Gene Therapy for Diseases of the Lung is an indispensable volume for pulmonologists, geneticists, molecular and cell biologists, oncologists, internists, physiologists, scientists involved in gene therapy, and graduate and medical school students in these disciplines.

Series Statement

Lung biology in health and disease ; 104

Uniform Title

Lung biology in health and disease ; v. 104.

Subjects

• Lung Diseases > therapy
• Lungs > Diseases > Gene therapy
• Genetic Therapy

Bibliography (note)

• Includes bibliographical references and index.

Contents

• Introduction / Claude Lenfant -- 1. Human Gene Therapy: The Initial Concepts / W. French Anderson -- 2. Discovering Genes That Cause Disease / Francis S. Collins -- 3. Adenoviral Vectors for Gene Therapy of Inherited and Acquired Disorders of the Lung / David T. Curiel and Robert I. Garver, Jr. -- 4. Adeno-Associated Virus-Based Delivery Systems / Pamela L. Zeitlin -- 5. Cellular Responses to Adenovirus Entry / Susanna Chiocca and Matthew Cotten -- 6. Cationic Lipid-Based Gene Delivery: An Update / Xiang Gao -- 7. Liposome/Viral Hybrid Gene Delivery Systems / Arlene A. Stecenko -- 8. Manipulating the Intracellular Trafficking of Nucleic Acids / Kathleen E. B. Meyer, Lisa S. Uyechi and Francis C. Szoka, Jr. -- 9. Delivery of Genes Through the Lung Circulation / David M. Rodman and Elizabeth G. Nabel -- 10. Targeting Gene Expression to the Lung / Jeffrey A. Whitsett and Stephan W. Glasser --
• 11. Strategies to Accomplish Targeted Gene Delivery Employing Tropism-Modified Adenoviral Vectors / Joanne T. Douglas and David T. Curiel -- 12. Toward Correction of the Genetic Defect in Cystic Fibrosis / Larry G. Johnson and Richard C. Boucher -- 13. Correction of the Genetic Defect in Alpha-1 Antitrypsin Deficiency by Somatic Gene Therapy / Randy C. Eisensmith and Savio L. C. Woo -- 14. Gene Therapy for Chronic Inflammatory Diseases of the Lungs / Angelo E. Canonico -- 15. Gene Therapy for Acute Diseases of the Lungs / Kenneth L. Brigham -- 16. Gene Therapy for Lung Cancer / Choon-Taek Lee and David P. Carbone -- 17. The Regulatory Process and Gene Therapy / Suzanne Epstein -- 18. Some Issues Affecting Progress Toward Human Gene Therapy and Potential Application to the Lung / Theodore Friedmann.

ISBN

0824700600 (hardcover : alk. paper)

LCCN

97007151

OCLC

• 36430935
• ocm36430935
• SCSB-4783011

Owning Institutions

Columbia University Libraries