Research Catalog

Title

New therapeutic agents in thrombosis and thrombolysis / edited by Arthur A. Sasahara, Joseph Loscalzo.

Publication

New York : M. Dekker, [1997], ©1997.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• Loscalzo, Joseph.
• Sasahara, Arthur A. (Arthur Asao), 1927-

Description

xiv, 681 pages : illustrations; 26 cm

Subjects

• Thrombosis
• Thrombolytic Therapy
• Fibrinolytic Agents
• Hemostasis > drug effects
• Thrombosis > drug therapy
• Fibrinolytic agents
• Thrombolytic therapy

Note

• Includes index.

Contents

• 1. Overview of Hemostasis and Fibrinolysis / Joseph Loscalzo and Andrew I. Schafer -- 2. A Survey of Animal Modes to Develop New and Novel Antithrombotic Agents / Walter Jeske, Demetra D. Callas and Brigitte Kaiser [et al.] -- 3. Experimental Strategies for Assessing Antithrombotic Benefits and Hemorrhagic Risks of Novel Antithrombotic Agents / Laurence A. Harker and Stephen R. Hanson -- 4. Design Issues in Clinical Trials of Thrombolytic and Antithrombotic Agents / Dina S. Stolman, Jay P. Siegel and Marc K. Walton [et al.] -- 5. Overview of New Developments in Heparins, Thrombin Inhibitors, and Other New and Novel Agents / Jeffrey I. Weitz and Jack Hirsh -- 6. Low-Molecular-Weight Heparins: Biochemistry and Pharmacology / Meyer Michel Samama and Pierre Claude Desnoyers -- 7. Low-Molecular-Weight Heparins: Prophylaxis of Venous Thrombosis / Vijay Vir Kakkar --
• 8. Low-Molecular-Weight Heparins: Treatment of Venous Thromboembolism / Philomeen M. M. Kuijer, Martin H. Prins and Harry Roger Buller -- 9. Direct Thrombin Inhibitors: Active-Site Inhibitors of Thrombin / Jules A. Shafer -- 10. Direct Thrombin Inhibitors in Venous Thromboembolism / Mark A. Crowther and Jeffrey S. Ginsberg -- 11. Direct Thrombin Inhibitors in Arterial Thrombosis / Bernard Rudolph Erickson and Eric Jeffrey Topol -- 12. Direct Thrombin Inhibitors: Hirulog / John M. Maraganore -- 13. Modulation of the Protein C Pathway as a Therapy for Thrombosis / Charles T. Esmon -- 14. Tissue Factor Pathway Inhibitor / Thomas J. Girard -- 15. Direct Factor Xa Inhibitors / George P. Vlasuk -- 16. Overview of Inhibition of Platelet Functions / James T. Willerson and Claude R. Benedict --
• 17. Pharmacology and Clinical Development of Abciximab (c7E3 Fab, ReoPro): A Monoclonal Antibody Inhibitor of GPIIb/IIIa and [actual symbol not reproducible] / Robert E. Jordan, Mary Ann Mascelli and Marian T. Nakada [et al.] -- 18. Clinical Use of a Monoclonal Antibody to the Platelet Glycoprotein IIb/IIIa Receptor / James J. Ferguson and James T. Willerson -- 19. Integrilin: Synthetic Peptides Against the Platelet Glycoprotein IIb/IIIa Receptor / Barbara E. Tardiff, Julie M. Miller and Robert A. Harrington [et al.] -- 20. Tirofiban, a Nonpeptide Inhibitor of the Platelet Glycoprotein IIb/IIIA Receptor / Lawrence I. Deckelbaum, Frederic L. Sax and William Grossman -- 21. Aurin Tricarboxylic Acid: Inhibitor of von Willebrand Factor Attachment to Platelet GPIb / Martin D. Phillips and Joel L. Moake -- 22. Antagonism of Platelet Glycoprotein Ib Receptors: Protective Effects in Injured Coronary Arteries / James T. Willerson --
• 23. Oxygen-Derived Free Radicals and Arterial Thrombosis / Paolo Golino -- 24. Platelet Procoagulant Activity / Permual Thiagarajan and Claude R. Benedict -- 25. Development of Unstable Angina and Myocardial Infarction: Importance of Platelets, Platelet- and Endothelium-Derived Mediators, and Monocytes/Macrophages in Thrombosis, Vasoconstriction, and Neointimal Proliferation / James T. Willerson -- 26. Introduction to the Section on New Thrombolytic Agents / Marc Verstraete -- 27. Animal Models to Assess the Safety and Efficacy of Thrombolytic Agents / Jean Marie Stassen -- 28. Biochemistry, Pharmacology, and Initial Clinical Experience with TNK-tPa / E. R. McCluskey, Bruce A. Keyt and Canio J. Refino [et al.] -- 29. Clinical and Preclinical Profile of the Novel Recombinant Plasminogen Activator Reteplase / Ulrich Martin -- 30. Recombinant Urokinase (r-UK): Biochemistry, Pharmacology, and Clinical Experience / R. Bruce Credo, Sandra E. Burke and Walter M. Barker [et al.] --
• 31. Pro-urokinase: History, Mechanisms of Action, and Clinical Development / Victor Gurewich -- 32. Recombinant Glycosylated Pro-urkinase: Biochemistry, Pharmacology, and Early Clinical Experience / R. Bruce Credo, Sandra E. Burke and Walter M. Barker [et al.] -- 33. Recombinant Staphylokinase for Thrombolytic Therapy / Steven Vanderschueren, Frans Van de Werf and Desire Collen -- 34. Desmodus rotundus (Vampire Bat) Plasminogen Activator [actual symbol not reproducible]: A Superior Thrombolytic Created by Evolution / Wolf-Dieter Schleuning, Akhileshwar Bhargava and Peter Donner -- 35. Antibody Targeting: A Strategy for Improving Thrombolytic Therapy / Edgar Haber -- 36. Thrombolytic Agents in Development / Marc Verstraete and Fedor Bachmann.

ISBN

082479866X (hardcover : alk. paper)

LCCN

97012542

Owning Institutions

Columbia University Libraries