Research Catalog

Molecular biology of multiple sclerosis / edited by W.C. Russell.

Title
Molecular biology of multiple sclerosis / edited by W.C. Russell.
Publication
Chichester ; New York : Wiley, [1997], ©1997.

Items in the Library & Off-site

Filter by

1 Item

StatusFormatAccessCall NumberItem Location
Request for On-site UseRequest Scan
How do I pick up this item and when will it be ready?
TextRequest in advance RC377 .M65 1997Off-site

Holdings

Details

Additional Authors
Russell, W. C.
Description
ix, 310 pages : illustrations; 24 cm
Summary
  • Multiple sclerosis (MS) is a devastating demyelinating disease with complex aetiology which defies simple molecular description. Molecular Biology of Multiple Sclerosis provides a compendium of information on the molecular aspects of the disease. It embraces contributions on the biology and pathology of the cells of the central nervous system as well as recent advances in our understanding of the relevant biochemistry, immunology, genetics and virology.
  • With this enhanced knowledge the prospects for transplantation and repair of the damaged myelin as well as approaches to rational therapy are considered. Studies in MS embrace a wide spectrum of disciplines and this volume will be indispensable to neurologists, molecular biologists, biochemists, microbiologists, geneticists and immunologists with an interest in MS.
Subject
  • Multiple Sclerosis > physiopathology
  • Multiple sclerosis > Molecular aspects
  • Neuroglia > physiology
Bibliography (note)
  • Includes bibliographical references and index.
Contents
  • 1. Multiple Sclerosis - a Molecular Conundrum / W. C. Russell -- 2. The Anatomical and Molecular Pathology of Multiple Sclerosis / I. V. Allen and J. Kirk -- 3. Molecular Cell Biology of Oligodendrocytes / K. R. Rogers, D. A. Vouyiouklis and P. J. Brophy -- 4. Molecular Biology of the Glia: Components of Myelin - Myelin Basic Protein - the Implication of Post-Translational Changes for Demyelinating Disease / D. D. Wood and M. A. Moscarello -- 5. Molecular Biology of the Glia: Components of Myelin - PLP and Minor Myelin Proteins / P. Montague and I. Griffiths -- 6. Molecular Biology of the Glia: Astrocytes / S. C. Lee and C. F. Brosnan -- 7. Molecular Biology of Microglia / M. L. Cuzner -- 8. Regulation of Transcription and Translation in the Central Nervous System / A. Asipu and G. E. Blair -- 9. The Blood-Brain Barrier / B. Engelhardt -- 10. B Cells and Autoimmunity / H. Link -- 11. T Cell Mediated Autoimmunity in Multiple Sclerosis / K. W. Wucherpfennig --
  • 12. Genetic Aspects of MS / A. Spurkland and F. Vartdal -- 13. Glycolipids of the CNS / M. Saito and R. K. Yu -- 14. Transplantation and Repair in Multiple Sclerosis / R. J. M. Franklin and C. ffrench-Constant -- 15. Viruses and MS / W. C. Russell -- 16. Animal Model Systems of MS / J. K. Fazakerley, S. Amor and A. A. Nash -- 17. Rational Therapy in Multiple Sclerosis / H. L. Weiner, M. J. Olek and M. J. Hohol [et al.].
ISBN
0471969664 (cased : alk. paper)
LCCN
96009436
Owning Institutions
Columbia University Libraries