Research Catalog

Title

The development of human gene therapy / edited by Theodore Friedmann.

Publication

Plainview, NY : Cold Spring Harbor Laboratory Press, c1999.

Items in the Library & Off-site

Details

Additional Authors

Friedmann, Theodore, 1935-

Description

xiii, 729 p. : ill.; 24 cm.

Series Statement

Cold Spring Harbor monograph series, 0270-1847 ; monograph 36

Uniform Title

Cold Spring Harbor monograph series ; 36.

Subject

• Gene therapy
• Human genetics
• Genetic Therapy
• Genetics, Medical

Bibliography (note)

• Includes bibliographical references and index.

Contents

• 1. The Origins, Evolution, and Directions of Human Gene Therapy / T. Friedmann -- 2. Retroviral Vectors / J.-K. Yee -- 3. Lentiviral Vectors / L. Naldini and I. M. Verma -- 4. Structure and Genetic Organization of Adenovirus Vectors / M. M. Hitt, R. J. Parks and F. L. Graham -- 5. Adenovirus Vectors / N. A. Wivel, G.-P. Gao and J. M. Wilson -- 6. Strategies to Adapt Adenoviral Vectors for Gene Therapy Applications: Targeting and Integration / P. N. Reynolds and D. T. Curiel -- 7. Adeno-associated Viral Vectors / R. J. Samulski, M. Sally and N. Muzyczka -- 8. Gene-transfer Tool: Herpes Simplex Virus Vectors / S. Laquerre, W. F. Goins and S. Moriuchi [et al.] -- 9. Emerging Viral Vectors / D. J. Jolly -- 10. Advances in Synthetic Gene-delivery System Technology / P. L. Felgner, O. Zelphati and X. Liang -- 11. Receptor-mediated Gene Delivery Strategies / M. Cotten and E. Wagner -- 12. Naked DNA Gene Transfer in Mammallan Cells / J. A. Wolff --
• 13. Delivery Systems and Adjuvants for DNA Vaccines / J. B. Ulmer and M. A. Liu -- 14. Targets for Gene Therapy / T. Friedmann and A. G. Motulsky -- 15. The Hematopoietic System as a Target for Gene Therapy / B. P. Sorrentino and A. W. Nienhuis -- 16. Cancer Immunotherapy / D. Pardoll and G. J. Nabel -- 17. Gene Transfer and Stem-cell Transplantation / M. K. Brenner -- 18. Suicide Genes: Gene Therapy Applications Using Enzyme/Prodrug Strategies / J. C. Morris, R. Touraine and O. Wildner [et al.] -- 19. The Logic of Anti-angiogenic Gene Therapy / J. Folkman, P. Hahnfeldt and L. Hlatky -- 20. Apoptosis as a Goal of Cancer Gene Therapy / J. C. Reed -- 21. Advances in Gene Therapy for HIV and Other Viral Infections / E. M. Poeschla and F. Wong-Staal -- 22. Progress toward Gene Therapy for Nervous System Diseases / A. Martinez-Serrano and A. Bjorklund --
• 23. Targeted Gene Repair in Mammalian Cells Using Chimeric RNA/DNA Oligonucleotides / E. B. Kmiec, B. T. Kren and C. J. Steer -- 24. Human Gene Therapy: Public Policy and Regulatory Issues / N. A. Wivel and W. F. Anderson -- 25. Ethical Issues in Human Gene Transfer Research / E. T. Juengst and L. Walters.

ISBN

0879695285

LCCN

98025205

OCLC

• 39235664
• ocm39235664
• SCSB-4786418

Owning Institutions

Columbia University Libraries