Research Catalog

Title

Statistics applied to clinical trials / Ton J. Cleophas ... [et al.].

Publication

Boston : Kluwer Academic Publishers, 2000.

Items in the Library & Off-site

Details

Additional Authors

Cleophas, Ton J. M.

Description

xi, 97 p. : ill.; 24 cm.

Summary

• "The present book not only explains classical statistical analyses of clinical trials, but also addresses relatively novel issues, including equivalence testing, interim analyses, sequential analyses, meta-analyses, and provides a framework of the best statistical methods currently available for such purpose.
• This book is not only useful for investigators involved in the field of clinical trials, but also for all physicians who wish to better understand the data of trials as published currently."--BOOK JACKET.

Subject

• Drugs > Testing > Statistical methods
• Clinical trials > Statistical methods
• Clinical Trials as Topic
• Data Interpretation, Statistical

Bibliography (note)

• Includes bibliographical references.

Contents

Ch. 1. Hypotheses, Data, Stratification -- Ch. 2. The Analysis of Efficacy Data of Drug Trials -- Ch. 3. The Analysis of Safety Data of Drug Trials -- Ch. 4. Equivalence Testing -- Ch. 5. Statistical Power and Sample Size -- Ch. 6. Interim Analysis -- Ch. 7. Multiple Statistical Inferences -- Ch. 8. Subgroup Analysis using Multiple Linear Regression: Confounding, Interaction, Synergism -- Ch. 9. Meta-Analysis -- Ch. 10. Capitum Selectum, Crossover Studies with Continuous Variables: Power Analysis -- Ch. 11. Capitum Selectum: Post-Hoc Analysis in Clinical Trials, a Case for Logistic Regression Analysis.

ISBN

0792361849 (pbk. : acid-free paper)

LCCN

00021727

OCLC

• 501488998
• ocn501488998
• SCSB-4788650

Owning Institutions

Columbia University Libraries