Research Catalog

Matrix metalloproteinase inhibitors in cancer therapy / edited by Neil J. Clendeninn and Krzysztof Appelt.

Title
Matrix metalloproteinase inhibitors in cancer therapy / edited by Neil J. Clendeninn and Krzysztof Appelt.
Publication
Totowa, N.J. : Humana Press, 2001.

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Additional Authors
  • Appelt, Krzysztof.
  • Clendeninn, Neil J.
Description
xi, 262 pages : illustrations (some color); 24 cm.
Series Statement
Cancer drug discovery and development
Uniform Title
Cancer drug discovery and development.
Subject
  • Antineoplastic agents
  • Extracellular Matrix > enzymology
  • Extracellular matrix proteins > Therapeutic use
  • Metalloendopeptidases > antagonists & inhibitors
  • Metalloendopeptidases > metabolism
  • Metalloproteinases > Therapeutic use
  • Neoplasms > drug therapy
Bibliography (note)
  • Includes bibliographical references and index.
Contents
  • 1. Biology and Regulation of the Matrix Metalloproteinases / Mark D. Sternlicht, Lisa M. Coussens and Thiennu H. Vu / [et al.] -- 2. Substrate Specificity of MMPs / Hideaki Nagase -- 3. The Tissue Inhibitors of Metalloproteinases (TIMPs): Biology and Regulation / Dylan R. Edwards -- 4. Matrix Metalloproteinases in Cancer / Barbara Fingleton and Lynn M. Matrisian -- 5. Hydroxamic Acid Matrix Metalloproteinase Inhibitors / Peter D. Brown, Alan H. Davidson and Alan H. Drummond / [et al.] -- 6. Prinomastat: A Potent and Selective Matrix Metalloprotease Inhibitor - Preclinical and Clinical Development for Oncology / David R. Shalinsky, Bhasker Shetty and Yazdi Pithavala / [et al.] -- 7. A Potent Nonpeptidic Matrix Metalloproteinase Inhibitor: Discovery of BAY 12-9566 / George Clemens, Barbara Hibner and Rachel Humphrey / [et al.] -- 8. D1927 and D2163: Novel Mercaptoamide Inhibitors of Matrix Metalloproteinases / A. D. Baxter, J. B. Bird and R. Bannister / [et al.] --
  • 9. Research on MMP Inhibitors with Unusual Scaffolds / Frank Grams, Hans Brandstetter and Richard A. Engh / [et al.] -- 10. Matrix Metalloproteinase Inhibitors: Therapeutic Applications Outside of Oncology / Michael R. Niesman.
ISBN
0896036685 (alk. paper)
LCCN
99089543
Owning Institutions
Columbia University Libraries