Research Catalog

Decoding darkness : the search for the genetic causes of Alzheimer's disease / Rudolph E. Tanzi, Ann B. Parson.

Title: Decoding darkness : the search for the genetic causes of Alzheimer's disease / Rudolph E. Tanzi, Ann B. Parson.
Author: Tanzi, Rudolph E.
Publication: Cambridge, Mass. : Perseus Publishing, [2000], ©2000.

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Status	Format	Access	Call Number	Item Location
Request for On-site Use Request Scan How do I pick up this item and when will it be ready?	Text	Request in advance	RC523.2 .D43 2000	Off-site

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Details

Additional Authors

Parson, Ann B.

Description

xviii, 281 pages, 8 unnumbered pages of plates : illustrations, portraits; 24 cm

Summary

"Working from the intriguing hypothesis that Alzheimer's dementia is the result of a renegade protein - beta amyloid - Tanzi and others set out to find the gene responsible for its production. Tanzi and science writer Ann Parson take us deep into the minds and far-flung labs of many a prominent researcher.
In the process, they offer an intimate view of the high stakes of molecular genetics, the revolution that propels it, the obstacles that threaten to derail it, and the families whose lives are so dependent upon it."--BOOK JACKET.

Subjects

Bibliography (note)

Includes bibliographical references and index.

Contents

1. Cleave, Zap, Blot, Probe -- 2. The Core of the Matter -- 3. Candidate Chromosome -- 4. Gone Fishing -- 5. Curious Gene -- 6. From Famine to Feast -- 7. Mutations, Revelations -- 8. Of Mice and People -- 9. Gene Prix -- 10. The 42 Nidus -- 11. Untangling a Cascade -- 12. A Gamble for Hope.

ISBN

0738201952 :

Owning Institutions

Columbia University Libraries