Research Catalog

Brain drug targeting : the future of brain drug development

Title
Brain drug targeting : the future of brain drug development / William M. Pardridge.
Author
Pardridge, William M.
Publication
New York : Cambridge University Press, 2001.

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TextUse in library RM301.63 .P37 2001Off-site

Details

Description
xvii, 353 p. : ill.; 26 cm.
Subject
  • Brain > metabolism
  • Central Nervous System Agents > pharmacokinetics
  • Blood-Brain Barrier > physiology
  • Drug Delivery Systems > methods
  • Drug Design
Bibliography (note)
  • Includes bibliographical references and index.
Contents
1. Drug targeting, drug discovery, and brain drug development -- 2. Invasive brain drug delivery -- 3. Lipid-mediated transport and carrier-mediated transport of small molecules -- 4. Receptor-mediated transcytosis of peptides -- 5. Vector discovery: genetically engineered Trojan horses for drug targeting -- 6. Linker strategies: the engineering of multifunctional drug formulations -- 7. Protein neurotherapeutics and peptide radiopharmaceuticals -- 8. Antisense neurotherapeutics and imaging gene expression in vivo -- 9. Gene therapy of the brain -- 10. Blood-brain barrier genomics.
ISBN
0521800773 (HB)
LCCN
00046764
OCLC
  • 46599999
  • ocm46599999
  • SCSB-4790846
Owning Institutions
Columbia University Libraries