Research Catalog

Title

RNA motifs and regulatory elements / Thomas Dandekar (ed.) ; with contributions by Peter Bengert ... [et al.].

Publication

New York : Springer, 2002.

Items in the Library & Off-site

Details

Additional Authors

• Dandekar, Thomas, 1960-
• Bengert, P. (Peter)

Description

233 p. : ill.; 24 cm.

Subjects

• Genetic regulation
• RNA, Messenger
• Regulatory Sequences, Nucleic Acid
• Messenger RNA
• RNA

Note

• Rev. ed. of: Regulatory RNA / Thomas Dandekar. 1998.

Bibliography (note)

• Includes bibliographical references and index.

Contents

• 1. Introduction. 1.1. Book Overview. 1.2. RNA, the Underestimated Molecule. 1.3. Examining Regulatory RNA Elements. 1.4. Regulation of Gene Expression. 1.5. Catalytic Active RNA. 1.6. Combination of RNA and Proteins. 1.7. RNA Motifs and Elements Indicate Conserved Function. 1.8. Context Specificity of RNA Within the Cell -- 2. Instances of Functional RNA. 2.1. Overview. 2.2. The Different Types of RNA and Their Regulatory Elements. 2.3. RNA Motifs Involved in Splicing. 2.4. RNA Editing. 2.5. Posttranscriptional Regulatory Signals in mRNA. 2.6. Further Regulatory RNAs. 2.7. Modified Residues in Eukaryotic mRNAs. 2.8. Correction of Missing Stop Codons by 10Sa-RNA. 2.9. Direct Regulation of Gene Expression. 2.10. Regulation of Prokaryotic Operons. 2.11. Cytoplasmic RNA Motifs. 2.12. Ribozymes and Their Motifs. 2.13. Viral RNA. 2.14. Other RNA Species. 2.15. A Catalogue of Regulatory RNA Motifs. 2.16. RNA Motifs in RNA Viridae.
• 2.17. Protein Motifs Pointing to Interacting RNA Structures. 2.18. Modified Nucleotides. 2.19. Perspective: from Known Instances to New Ones. 2.20. An Atlas of Regulatory RNA Elements -- 3. Experimental Identification of New Functional RNA. 3.1. Introduction. 3.2. Typical Challenges. 3.3. Cellular Regulation. 3.4. Confirmation of RNA Functionality -- 4. Computer-Based and Theoretical Identification of Regulatory RNA. 4.1. Introduction. 4.2. Carrying Out an RNA Motif Search. 4.3. Example Searches. 4.4. Motif Specific Searches for RNA Elements. 4.5. General-Purpose Search Programs. 4.6. Evaluation of the Search Result -- 5. Functional RNA Interactions. 5.1. Introduction. 5.2. Cellular Information Transfer from mRNA. 5.3. Catalytic RNA. 5.4. RNA Motif Evolution. 5.5. RNA-Protein Interactions. 5.6. Designing Interactions. 5.7. Medical Implications. 5.8. Perspectives -- 6. Areas of Research on RNA Motifs and Regulatory Elements. 6.1. Introduction.
• 6.2. The Transcription of DNA. 6.3. The Splicing of Messenger RNA. 6.4. Trans-Splicing. 6.5. RNA Editing. 6.6. Ribosomal RNA Processing Steps. 6.7. Nuclear RNA Transport. 6.8. Regulatory Motifs in mRNA. 6.9. Posttranscriptional Gene Silencing and RNA Interference. 6.10. Catalytic RNA and Motifs. 6.11. Viral RNAs -- 7. Outlook. 7.1. New Types and Classes of Regulatory RNAs Come up at an Unprecedented Pace. 7.2. Established Areas of Research. 7.3. Conclusion -- 8. Figure-Acknowledgement -- 9. References -- 10. Subject Index.

ISBN

354041701X (hardcover : alk. paper)

LCCN

2001020337

OCLC

• 501491647
• ocn501491647
• SCSB-4791629

Owning Institutions

Columbia University Libraries