Research Catalog

Title

Tumor-suppressing viruses, genes, and drugs : innovative cancer therapy approaches / edited by Hiroshi Maruta.

Publication

San Diego : Academic Press, [2002], ©2002.

Items in the Library & Off-site

Details

Additional Authors

Maruta, Hiroshi.

Description

xv, 425 pages : illustrations; 24 cm

Subject

• Anticarcinogenic Agents
• Antioncogenes
• Cancer > Gene therapy
• Cancer > Molecular aspects
• Cancer > Technological innovations
• Genetic Therapy
• Neoplasms > therapy
• Neoplasms > virology
• Viruses > Therapeutic use

Bibliography (note)

• Includes bibliographical references and index.

Contents

• 1. Oncolytic Viruses: Virotherapy for Cancer / Lynda K. Hawkins and David Kirn -- 2. Reovirus Therapy of Ras-Associated Cancers / Patrick W. K. Lee -- 3. Oncolytic Herpes Simplex Virus (G207) Therapy: From Basic to Clinical / Tomoki Todo, Michael I. Ebright and Yuman Fong / [et al.] -- 4. p53 and Its Targets / Rishu Takimoto and Wafik S. El-Deiry -- 5. Prospects for Tumor Suppressor Gene Therapy: RB as an Example / Daniel J. Riley and Wen-Hwa Lee -- 6. CDK Inhibitors: Genes and Drugs / Jun-ya Kato, Kiichiro Tomoda and Yukinobu Arata / [et al.] -- 7. CDK Inhibitors: Small Molecular Weight Compounds / Laurent Meijer and Eve Damiens -- 8. NF1 and Other RAS-Binding Peptides / Hiroshi Maruta -- 9. Cytoskeletal Tumor Suppressor Genes / Noboru Kuzumaki and Hiroshi Maruta -- 10. TGF-[beta] Signaling and Carcinogenesis / Masahiro Kawabata -- 11. DAN Gene / Shigeru Sakiyama --
• 12. Design of Hammerhead Ribozymes and Allosterically Controllable Maxizymes for Cancer Gene Therapy / Hiroaki Kawasaki, Tomoko Kuwabara and Kazunari Taira -- 13. Inhibitors of Angiogenesis / Steven A. Stacker and Marc G. Achen -- 14. Geranylgeranylated RhoB Mediates the Apoptotic and Antineoplastic Effects of Farnesyltransferase Inbitors: New Insights into Cancer Cell Suicide / George C. Prendergast -- 15. RAS Binding Compounds / Oliver Muller and Alfred Wittinghofer -- 16. Actin-Binding Drugs: MKT-077 and Chaetoglobosin K(CK) / Hiroshi Maruta -- 17. Tyr Kinase Inhibitors as Potential Anticancer Agents: EGF Receptor and ABL Kinases / Antony W. Burgess -- 18. Antagonists of Rho Family GTPases: Blocking PAKs, ACKs, and Rock / Hiroshi Maruta, Hong He and Thao Nheu -- 19. Integrin Antagonists as Cancer Therapeutics / Chandra C. Kumar and Lydia Armstrong -- 20. Functional Rescue of Mutant p53 as a Strategy to Combat Cancer / Galina Selivanova and Klas G. Wiman.

ISBN

0124762492 (alk. paper)

LCCN

2001095847

Owning Institutions

Columbia University Libraries