Research Catalog
Molecular biology in medicinal chemistry
- Title
- Molecular biology in medicinal chemistry / edited by Th. Dingermann, D. Steinhilber and G. Folkers.
- Publication
- Weinheim : Wiley-VCH, c2004.
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| Status | Format | Access | Call Number | Item Location |
|---|---|---|---|---|
Not available - Please for assistance. | Text | Use in library | RM301.65 .M636 2004g | Off-site |
Details
- Additional Authors
- Description
- xxi, 413 p. : ill.; 24 cm.
- Summary
- Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action.
- Series Statement
- Methods and principles in medical chemistry ; v. 21
- Uniform Title
- Methods and principles in medicinal chemistry ; v. 21.
- Subjects
- Bibliography (note)
- Includes bibliographical references and index.
- Contents
- Cellular assays in drug discovery -- Gene knockout models -- Reporter gene assay systems for the investigation of GPCRs -- From the human genome to new drugs: The potential of orphan GPCRs -- Stereoselective synthesis with the help of recombinant enzymes -- Nucleic acid drugs -- Recent trends in enantioseparation of chiral drugs -- Affinity chromatography -- NMR-based drug discovery -- 13C- and 15N-Isotopic labeling of proteins -- Antibody fragments as crystallization enhancers -- Pharmacogenetics: the effect of inherited henetic variation on drug disposition and drug response -- Pharmacogenomics of bioavailability and elimination -- Toxicogenomics: integration of new molecular biological tools in toxicology.
- ISBN
- 3527304312
- OCLC
- 55056137
- ocm55056137
- SCSB-4877520
- Owning Institutions
- Columbia University Libraries