Research Catalog

Title

Enantioselective synthesis of [beta]-amino acids / edited by Eusebio Juaristi, Vadim A. Soloshonok.

Publication

Hoboken, N.J. : Wiley, [2005], ©2005.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• Juaristi, Eusebio.
• Soloshonok, V. A.

Description

xx, 634 pages : illustrations; 25 cm

Summary

"This Second Edition of Enantioselective Synthesis of [beta]-Amino Acids updates reviews included in the First Edition while also covering new developments since its publication. The book presents detailed discussions of the most important methods for the synthesis of [beta]-amino acids. In most cases, the lead chemist who originally developed a method provides an authoritative description of it." "The only book of its kind available today, Enantioselective Synthesis of [beta]-Amino Acids, Second Edition offers upper-level students and professionals an essential resource for pharmaceutical development, medicinal chemistry, and biochemistry."--BOOK JACKET.

Subjects

• Chiral drugs > Synthesis
• Beta lactam antibiotics > Synthesis
• Amino acids > Synthesis
• Enantiomers > Synthesis

Bibliography (note)

• Includes bibliographical references and index.

Contents

1. Structural types of relevant [beta]-amino acid targets / Eusebio Juaristi -- 2. [beta]-amino acids in natural products / Peter Spiteller and Franz von Nussbaum -- 3. Preparation of enantiopure [beta]-amino acids by homologation of [alpha]-amino acids / Joachim Podlech -- 4. Asymmetric catalysis in enantioselective synthesis of [beta]-amino acids / Anna G. Wenzel and Eric N. Jacobsen -- 5. Enantioselective synthesis of conformationally constrained [beta]-amino acids / Rosa M. Ortuno -- 6. Catalytic enantioselective Mannich reactions / Masaharu Ueno and Shu Kobayashi -- 7. Enantioselective synthesis of [beta]-amino acids via stereoselective hydrogenation of [beta]-aminoacrylic acid derivatives / Eusebia Juaristi, Victor Manuel Gutierrez-Garcia and Heraclio Lopez-Ruiz -- 8. Asymmetric synthesis of [beta]-amino acids by enolate additions to tert-butanesulfinyl imines / Kristin Brinner and Jonathan A. Ellman -- 9. Organocatalytic approaches to enantioenriched [beta]-amino acids / Fujie Tanaka and Carlos F. Barbas III -- 10. Asymmetric synthesis of cycle [beta]-amino acids via cycloaddition reactions / Jose Barluenga, Bernardo Olano, Josefa Florez and Carlos Valdes -- 11. Enantioselective synthesis of novel [beta]-amino acids / Javed Iqbal and Saibal Kumar Das -- 12. Asymmetric synthesis of phosphonic analogs of [beta]-amino acids / Marian Mikolajczyk, Jozef Drabowicz and Piotr Lyzwa -- 13. Asymmetric synthesis of [alpha]-substituted-[beta]-amino phosphonates and phosphinates and [beta]-amino sulfur analogs / Francisco Palacios, Concepcion Alonso and Jesus de los Santos -- 14. Stereoselective synthesis of fluorine-containing [beta]-amino acids / Santos Fustero, Juan F. Sanz-Cervera and Vadim A. Soloshonok -- 15. Enantioselective synthesis of [beta]-amino acids via conjugate addition to [alpha], [beta]-unsaturated carbonyl compounds / Scott J. Miller and David J. Guerin -- 16. Preparation of enantiopure [beta]-amino acids via enantioselective conjugate addition / Mei Liu and Mukund P. Sibi -- 17. Biocatalytic entry to enantiomerically pure [beta]-amino acids / Dmitrii O. Berbasov, Trevor K. Ellis and Vadim A. Soloshanok -- 18. Stereoselective synthesis of [beta]-amino acids via radical reactions / Takeaki Naito and Okiko Miyata -- 19. Recent advances in synthesis of [alpha]-hydroxy-[beta]-amino acids and their use in SAR studies of taxane anticancer agents / Jin Chen, Larisa V. Kuznetsova, Ioana M. Ungreanu and Iwao Ojima -- 20. Synthesis of [beta]-amino acids and their derivatives from [beta]-lactams : update / Claudio Palomo, Jesus M. Aizpurua, Inaki Ganboa and Mikel Oiarbide -- 21. Multiple-component condensation methods for preparation of combinatorial libraries of [beta]-amino carbonyl derivatives / James C. Adrian, Jr. -- 22. Using constrained [beta]-amino acid residues to control [beta]-peptide shape and function / Michael A. Gelman and Samuel H. Gellman -- 23. [beta][superscript 2]-amino acids with proteinogenic side chains and corresponding peptides : synthesis, secondary structure, and biological activity / Marino A. Campo, Jaime Escalante and Radovan Sebesta.

ISBN

0471467383 (cloth)

LCCN

2004010498

OCLC

• ocm55124555
• SCSB-5183931

Owning Institutions

Columbia University Libraries