Research Catalog
DNA methylation and cancer therapy
- Title
- DNA methylation and cancer therapy / [edited by] Moshe Szyf.
- Publication
- Georgetown, Tex. : Landes Bioscience/Eurekah.com ; New York, N.Y. : Kluwer Academic/Plenum, [2005], ©2005.
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2 Items
| Status | Format | Access | Call Number | Item Location |
|---|---|---|---|---|
| Text | Request in advance | QP624.5.M46 D625 2005 | Off-site | |
Not available - Please for assistance. | Text | Use in library | Off-site |
Holdings
Details
- Additional Authors
- Szyf, Moshe.
- Description
- 239 pages : illustrations; 24 cm.
- Series Statement
- Medical intelligence unit
- Uniform Title
- Medical intelligence unit (Unnumbered : 2003)
- Subjects
- Bibliography (note)
- Includes bibliographical references and index.
- Contents
- 1. DNA methylation : three decades in search of function / Aharon Razin -- 2. Epigenetic mechanisms of gene regulation : relationships between DNA methylation, histone modification, and chromatin structure / Keith D. Robertson -- 3. DNA hypo- vs. hypermethylation in cancer : tumor specificity, tumor progression, and therapeutic implications / Melanie Ehrlich and Guanchao Jiang -- 4. DNA methylation in urological cancers / Wolfgang A. Schulz and Hans-Helge Seifert -- 5. DNA methylation in colorectal cancer / Jeremy R. Jass, Vicki L. J. Whitehall, Joanne Young and Barbara A. Leggett -- 6. CpG island hypermethylation of tumor suppressor genes in human cancer : concepts, methodologies and uses / Michel Herranz and Manel Esteller -- 7. The loss of methyl groups in DNA of tumor cells and tissues : the immunochemical approach / Alain Niveleau, Chandrika Piyathilake, Adriana de Capoa, Claudio Grappelli, Jean-Marc Dumollard, Lucien Frappart and Emmanuel Drouet -- 8. Identifying clinicopathological association of DNA hypermethylation in cancers using CpG island microarrays / Susan H. Wei, Timothy T.-C. Yip, Chuan-Mu Chen and Tim H.-M. Huang -- 9. Methylation analysis in cancer : (epi)genomic fast track from discovery to clinical routine / Carolina Haefliger, Sabine Maier and Alexander Olek -- 10. Regulation of DNA methyltransferases in cancer / Nancy Detich and Moshe Szyf -- 11. Inhibition of poly(ADP-ribosyl)action allows DNA hypermethylation / Anna Reale, Giuseppe Zardo, Maria Malanga, Jordanka Zlatanova and Paola Caiafa -- 12. The role of active demethylation in cancer and its therapeutic potential / Moshe Szyf, Paul M. Campbell, Nancy Detich, Jing Ni Ou, Stefan Hamm and Veronica Bovenzi -- 13. Purine analogues and their role in methylation and cancer chemotherapy / Katherine L. Seley and Sylvester L. Mosley -- 14. DNA methyltransferase inhibitors : paving the way for epigenetic cancer therapeutics / Gregory K. Reid and A. Robert MacLeod -- 15. Preclinical and clinical studies on 5-Aza-2'-deoxycytidine, a potent inhibitor of DNA methylation, in cancer therapy / Richard L. Momparler -- 16. Anticancer gene therapy by in vivo DNA electrotransfer of MBD2 antisense / Pascal Bigey and Daniel Scherman -- Epilogue / Moshe Szyf.
- ISBN
- 030647848X
- LCCN
- 2004022708
- OCLC
- ocm56614483
- SCSB-5190205
- Owning Institutions
- Columbia University Libraries