Research Catalog

Protein tyrosine kinases : from inhibitors to useful drugs

Title
Protein tyrosine kinases : from inhibitors to useful drugs / edited by Doriano Fabbro and Frank McCormick.
Publication
Totowa, N.J. : Humana Press, [2006], ©2006.

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TextRequest in advance RC271.P76 P76 2006Off-site
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Details

Additional Authors
  • Fabbro, D.
  • McCormick, Frank, 1950-
Description
xiii, 290 pages : illustrations (some color); 24 cm.
Series Statement
Cancer drug discovery and development
Uniform Title
Cancer drug discovery and development.
Subjects
Bibliography (note)
  • Includes bibliographical references and index.
Contents
1. Protein tyrosine kinases as targets for cancer and other indications / Mark Pearson, Carlos Garcia-Echeverria and Doriano Fabbro -- 2. Inhibitors of signaling interfaces : targeting Src homology 2 domains in drug discovery / Carlos Garcia-Echeverria -- 3. PI3-kinase inhibition : a target for therapeutic intervention / Peter M. Finan and Stephen G. Ward -- 4. Src as a target for pharmaceutical intervention : potential and limitations / Mira Susa, Martin Missbach, Rainer Gamse, Michaela Kneissel, Thomas Buhl, Jurg A. Gasser, Markus Glatt, Terence O'Reilly, Anna Teti and Jonathan Green -- 5. Activated FLT3 receptor tyrosine kinase as a therapeutic target in leukemia / Blanca Scheijen and James D. Griffin -- 6. JAK kinases in leukemias, lymphomas, and multiple myeloma / Renate Burger and Martin Gramatzki -- 7. Glivec (Gleevec, Imatinib, STI571) : a targeted therapy for chronic myelogenous leukemia / Elisabeth Buchdunger and Renaud Capedeville -- 8. Platelet-derived growth factor : normal function, role in disease, and application of PDGF antagonists / Tobias Sjoblom, Kristian Pietras, Arne Ostman and Carl-Henrik Heldin -- 9. Structural biology of protein tyrosine kinases / Sandra W. Cowan-Jacob, Paul Ramage, Wilhelm Stark, Gabriele Fendrich and Wolfgang Jahnke -- 10. Testing of signal transduction inhibitors in animal models of cancer / Terence O'Reilly and Robert Cozens -- 11. Phosphoproteomics in drug discovery and development / Michel F. Moran, Jarrod A. Marto, Cynthia J. Brame, Olga Ornatsky, Mark M. Ross, Leticia M. Toledo-Sherman, Alfredo C. Castro, Brett Larsen, Henry Duewel, Christopher Hosfield, Christopher Orsi, Thodoros Topaloglou, Daniel Figeys, Jennifer A. Caldwell-Busby and David R. Stover.
ISBN
158829384X (alk. paper)
LCCN
2005006248
OCLC
  • ocm58452142
  • SCSB-5216302
Owning Institutions
Columbia University Libraries