Research Catalog

Title

Alzheimer's disease : cellular and molecular aspects of amyloid [beta] / edited by J. Robin Harris and Falk Fahrenholz.

Publication

New York : Springer, [2005], ©2005.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• Harris, James R.
• Fahrenholz, F. (Falk)

Description

xv, 409 pages : illustrations; 24 cm.

Summary

"The volume contains a broad range of current information on cellular, biochemical, and structural aspects of amyloid-[beta], of direct relevance to Alzheimer's disease."--BOOK JACKET.

Series Statement

Sub-cellular biochemistry, 0306-0225 ; v. 38

Uniform Title

Sub-cellular biochemistry ; v. 38.

Subject

• Alzheimer's disease
• Amyloid beta-protein
• Alzheimer Disease
• Amyloid beta-Peptides

Bibliography (note)

• Includes bibliographical references and index.

Contents

1. The contribution of microscopy to the study of amyloid plaques and to amyloid-[beta] fibrillogenesis / J. Robin Harris -- 2. Transgenic mouse models for APP processing and Alzheimer's disease : early and late defects / Tom Van Dooren, Ilse Dewachter, Peter Borghgraef and Fred Van Leuven -- 3. Oxidative stress in Alzheimer's disease : implications for prevention and therapy / Christian Behl -- 4. [beta]-secretase, APP and A[beta] in Alzheimer's disease / Robert Vassar -- 5. The non-amyloidogenic pathway : structure and function of [alpha]-secretases / Elzbieta Kojro and Falk Fahrenholz -- 6. Amyloid [beta] degradation : a challenging task for brain peptidases / Laura Morelli, Ayelen Bulloj, Maria Celeste Leal and Eduardo M. Castano -- 7. The protective role of vitamin E in vascular amyloid [beta]-mediated damage / Francisco Jose Munoz, Montserrat Sole and Mireia Coma -- 8. Amyloid accumulation and pathogenesis of Alzheimer's disease : significance of monomeric, oligomeric and fibrillar A[beta] / Charles C. Glabe -- 9. Cholesterol and amyloid [beta] fibrillogenesis / Katsuhiko Yanagisawa -- 10. Alzheimer's [beta]-amyloid : insights into fibril formation and structure from congo red binding / Hideyo Inouye and Daniel A. Kirschner -- 11. The aluminium-amyloid cascade hypothesis and Alzheimer's disease / Christopher Exley -- 12. Amyloid-[beta] metal interaction and metal chelation / Math P. Cuajungco, Christopher J. Frederickson and Ashley I. Bush -- 13. The interaction of amyloid-[beta] with ApoE / Donald B. Carter -- 14. Clusterin and Alzheimer's disease / Miguel Calero, Agueda Rostagno, Blas Frangione and Jorge Ghiso -- 15. Acetylcholinesterase interaction with Alzheimer amyloid [beta] / Nibaldo C. Inestrosa, Juan Paulo Sagal and Marcela Colombres -- 16. Membrane disordering effects of [beta]-amyloid peptides / Gunter P. Eckert, W. G. Wood and Werner E. Muller -- 17. The role of Alzheimer A[beta] peptides in ion transport across cell membranes / Vernon M. Ingram -- 18. Amyloid inhibitors and [beta]-sheet breakers / Claudio Soto and Lisbell Estrada -- 19. Cholesterol and Alzheimer's disease : statins, cholesterol depletion in APP processing and A[beta] generation / Tobias Hartmann -- 20. Phosphorylated amyloid-[beta] : the toxic intermediate in Alzheimer's disease neurodegeneration / Nathaniel G. N. Milton.

ISBN

0387232257

OCLC

• ocm57451595
• SCSB-5227616

Owning Institutions

Columbia University Libraries