Research Catalog

Title

DNA repair and mutagenesis / Errol C. Friedberg [and others].

Publication

Washington, D.C. : ASM Press, [2006], ©2006.

Items in the Library & Off-site

Holdings

Details

Additional Authors

Friedberg, Errol C.

Description

xxix, 1118 pages : illustrations (some color); 29 cm

Subject

• DNA repair
• Mutagenesis

Note

• Rev. ed. of: DNA repair and mutagenesis / Errol C. Friedberg, Graham C. Walker, Wolfram Siede. c1995.

Bibliography (note)

• Includes bibliographical references and index.

Contents

1. Introduction : biological responses to DNA damage -- 2. DNA damage -- 3. Introduction to mutagenesis -- 4. Reversal of base damage caused by UV radiation -- 5. Reversal of alkylation damage in DNA -- 6. Base excision repair -- 7. Nucleotide excision repair : general features and the process in prokaryotes -- 8. Nucleotide excision repair in eukaryotes : cell biology and genetics -- 9. Mechanism of nucleotide excision repair in eukaryotes -- 10. Heterogeneity of nucleotide excision repair in eukaryotic genomes -- 11. Alternative excision repair of DNA -- 12. Mismatch repair -- 13. Repair of mitochondrial DNA damage -- 14. The SOS responses of prokaryotes to DNA damage -- 15. Mutagenesis and translesion synthesis in prokaryotes -- 16. Recombinational repair, replication fork repair, and DNA damage tolerance -- 17. DNA damage tolerance and mutagenesis in eukaryotic cells -- 18. Managing DNA strand breaks in eukaryotic cells : repair pathway overview and homologous recombination -- 19. Managing DNA strand breaks in eukaryotic cells : nonhomologous end joining and other pathways -- 20. Cell cycle checkpoints : general introduction and mechanisms of DNA damage sensing -- 21. Cell cycle checkpoints : signal transmission and effector targets -- 22. Transcriptional responses to DNA damage -- 23. DNA damage and the regulation of cell fate -- 24. Xeroderma pigmentosum : a disease associated with defective nucleotide excision repair or defective translesion DNA synthesis -- 25. Other diseases associated with defects in nucleotide excision repair of DNA -- 26. Diseases associated with defective responses to DNA strand breaks -- 27. Diseases associated with disordered DNA helicase function -- 28. Additional diseases associated with defective responses to DNA damage -- 29. Hereditary diseases that implicate defective responses to DNA damage -- 30. DNA polymorphisms in gatekeeper and guardian genes.

ISBN

1555813194

LCCN

2005045353

OCLC

• ocm59360087
• SCSB-5230161

Owning Institutions

Columbia University Libraries