Research Catalog
Anticancer agents from natural products
- Title
- Anticancer agents from natural products / edited by Gordon M. Cragg, David G.I. Kingston, David J. Newman.
- Publication
- Boca Raton, Fla. : Taylor & Francis, 2005.
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| Status | Format | Access | Call Number | Item Location |
|---|---|---|---|---|
| Text | Request in advance | RS431.A64 A562 2005 | Off-site |
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Details
- Additional Authors
- Description
- 577 pages : illustrations (some color); 26 cm
- Summary
- "Anticancer Agents from Natural Products analyzes current clinically used anticancer agents that are natural products or clearly derived from natural product leads. Edited by leading scientists who have contributed enormously to natural product development and potential anticancer natural products, Anticancer Agents from Natural Products is a convenient summary of the current status of research and development of some of the most effective anticancer agents available today. It is an ideal foundation for scientists engaged in developing new and improved drugs based on natural sources."--BOOK JACKET.
- Subjects
- Bibliography (note)
- Includes bibliographical references and index.
- Contents
- Ch. 1. Introduction / Gordon M. Cragg, David G. I. Kingston and David J. Newman -- Ch. 2. Champtothecin and its analogs / Nicolas J. Rahier, Craig J. Thomas and Sidney M. Hecht -- Ch. 3. The discovery and development of the combretastatins / Kevin G. Pinney, Christopher Jelinek, Klaus Edvardsen, David J. Chaplin and George R. Pettit -- Ch. 4. Homoharringtonine and related compounds / Hideji Itokawa, Xihong Wang and Kuo-Hsiung Lee -- Ch. 5. Podophyllotoxins and analogs / Kuo-Hsiung Lee and Zhiyan Xiao -- Ch. 6. Taxol and its analogs / David G. I. Kingston -- Ch. 7. The vinca alkaloids / Francoise Gueritte and Jacques Fahy -- Ch. 8. The bryostatins / David J. Newman -- Ch. 9. The isolation, characterization, and development of a novel class of potent antimitotic macrocyclic depsipeptides : the cryptophycins / Rima S. Al-awar and Chuan Shih -- Ch. 10. Chemistry and biology of the discodermolides, potent mitotic spindle poisons / Sarath P. Gunasekera and Amy E. Wright -- Ch. 11. The dolastatins : novel antitumor agents from Dolabella auricularia / Erik Flahive and Jayaram Srirangam -- Ch. 12. Ecteinascidin 743 (ET-743; Yondelis), aplidin, and kahalaide F / Ruben Henriquez, Glynn Faircloth and Carmen Cuevas -- Ch. 13. Discovery of E7389, a fully synthetic macrocyclic ketone analog of halichondrin B / Melvin J. Yu, Yoshito Kishi and Bruce A. Littlefield -- Ch. 14. HTI-286, a synthetic analog of the antimitotic natural product hemiasterlin / Raymond J. Andersen and Michel Roberge -- Ch. 15. The actinomycins / Anthony B. Mauger and Helmut Lackner -- Ch. 16. Anthracyclines / Federico Maria Arcamone -- Ch. 17. Ansamitocins (maytansinoids) / Tin-Wein Yu and Heinz G. Floss -- Ch. 18. Benzoquinone ansamycins / Kenneth M. Snader -- Ch. 19. Bleomycin group antitumor agents / Sidney M. Hecht -- Ch. 20. Biochemical and biological evaluation of (+)-CC-1065 analogs and conjugates with polyamides / Rohtash Kumar and J. William Lown -- Ch. 21. Epothilone, a myxobacterial metabolite with promising antitumor activity / Gerhard Hofle and Hans Reichenbach -- Ch. 22. Enediynes / Philip R. Hamann, Janis Upeslacis and Donald B. Borders -- Ch. 23. The mitomycins / William A. Remers -- Ch. 24. Staurosporines and structurally related indolocarbazoles as antitumor agents / Michelle Prudhomme -- Ch. 25. Combinatorial biosynthesis of anticancer natural products / Michael G. Thomas, Kathryn A. Bixby and Ben Shen -- Ch. 26. Developments and future trends in anticancer natural products drug discovery / David J. Newman and Gordon M. Cragg.
- ISBN
- 0849318637
- LCCN
- 2004065568
- OCLC
- ocm57169963
- SCSB-5239018
- Owning Institutions
- Columbia University Libraries