Research Catalog
Integrated strategies for drug discovery using mass spectrometry
- Title
- Integrated strategies for drug discovery using mass spectrometry / [edited by] Mike S. Lee.
- Publication
- Hoboken, N.J. : Wiley-Interscience, [2005], ©2005.
- Supplementary Content
Items in the Library & Off-site
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2 Items
Status | Format | Access | Call Number | Item Location |
---|---|---|---|---|
Text | Request in advance | RS189.5.S65 I55 2005 | Off-site | |
Not available - Please for assistance. | Text | Use in library | Off-site |
Holdings
Details
- Additional Authors
- Lee, Mike S., 1960-
- Description
- xvii, 550 pages : illustrations; 24 cm
- Subjects
- Bibliography (note)
- Includes bibliographical references and index.
- Contents
- 1. Miniaturized formats for efficient liquid chromatography mass spectrometry-based proteomics and therapeutic development / Gary A. Valaskovic and Neil L. Kelleher -- 2. Mass-spectrometry-based drug screening assays for early phases in drug discovery / Marshall M. Siegel -- 3. ESI-FTICR as a high throughput drug discovery platform / Kristin A. Sannes-Lowery, Lendell L. Cummins, Shuo Chen, Jared J. Drader and Steven A. Hofstadler -- 4. Mass spectrometry-based proteomic approaches for disease diagnosis and biomarker discovery / Thomas P. Conrads, Haleem J. Isaaq, Josip S. Blonder and Timothy D. Veenstra -- 5. Metabonomic applications in toxicity screening and disease diagnosis / John P. Shockcor and Elaine Holmes -- 6. The central role of mass spectrometry in natural products discovery / Jeffrey R. Gilbert, Paul Lewer, Dennis O. Duebelbeis and Andrew W. Carr -- 7. Application of mass spectrometry to compound library generation, analysis, and management / Xueheng Cheng and Jill Hochlowski -- 8. A combinatorial process for drug discovery / David S. Wagner, Richard W. Wagner, Frank Schoenen and H. Mario Geysen -- 9. Application of technological advances in biotransformation studies / Carmen L. Fernandez-Metzler, Raju Subramanian and Richard C. King -- 10. Applications of mass spectrometry for the characterization of reactive metabolites of drugs in discovery / Jim Wang, Jack Wang, Margaret Davis, William DeMaio, JoAnn Scatina and Rasmy Talaat -- 11. Advances in high throughput quantitative drug discovery bioanalysis / Bradley L. Ackermann, Michael J. Berna and Anthony T. Murphy -- 12. New strategies for the implementation and support of bioanalysis in a drug metabolism environment / Walter A. Korfmacher -- 13. An integrated LC-MS strategy for preclinical candidate optimization / Jonathan L. Josephs and Mark Sanders -- 14. New approaches for method development and purification in lead optimization / Yining Zhao and David J. Semin -- 15. High throughput metabolic and physicochemical property analysis : strategies and tactics for impact on drug discovery success / Edward H. Kerns and Li Di -- 16. Organ perfusion and mass spectrometry / C. Gerald Curtis, Ben Chien, David Bar-Or and Kumar Ramu -- 17. Sample preparation for drug discovery bioanalysis / David A. Wells -- 18. Automation / John D. Laycock and Thomas Hartmann.
- ISBN
- 047146127X (cloth)
- LCCN
- 2005003235
- 9780471461272
- OCLC
- ocm57579301
- SCSB-5240496
- Owning Institutions
- Columbia University Libraries