Research Catalog

Natural products : drug discovery and therapeutic medicine

Title
Natural products : drug discovery and therapeutic medicine / edited by Lixin Zhang, Arnold L. Demain.
Publication
Totowa, N.J. : Humana Press, [2005], ©2005.

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TextRequest in advance RS160 .N38 2005Off-site
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Details

Additional Authors
  • Zhang, Lixin, Ph. D.
  • Demain, A. L. (Arnold L.), 1927-
Description
xiv, 382 pages : illustrations; 26 cm
Subjects
Bibliography (note)
  • Includes bibliographical references and index.
Contents
1. Natural products and drug discovery / Arnold L. Demain and Lixin Zhang -- 2. Integrated approaches for discovering novel drugs from microbial natural products / Lixin Zhang -- 3. Automated analyses of HPLC profiles of microbial extracts : a new tool for drug discovery screening / Jose R. Tormo and Juan B. Garcia -- 4. Manipulating microbial metabolites for drug discovery and production / C. Richard Hutchinson -- 5. Improving drug discovery from microorganisms / Chris M. Farnet and Emmanuel Zazopoulos -- 6. Developments in strain improvement technology : evolutionary engineering of industrial microorganisms through gene, pathway, and genome shuffling / Stephen B. del Cardayre -- 7. The discovery of anticancer drugs form natural sources / David J. Newman and Gordon M. Cragg -- 8. Case studies in natural-product optimization : novel antitumor agents derived from taxus brevifolia and catharanthus roseus / Jian Hong and Shu-Hui Chen -- 9. Terpenoids as therapeutic drugs and pharmaceutical agents / Guangyi Wang, Weiping Tang and Robert R. Bidigare -- 10. Challenges and opportunities in the Chinese herbal drug industry / Wei Jia and Lixin Zhang -- 11. Arsenic trioxide and leukemia : from bedside to bench / Guo-Qiang Chen, Qiong Wang, Hua Yan and Zhu Chen -- 12. New methods to access microbial diversity for small molecule discovery / Karsten Zengler, Ashish Paradkar and Martin Keller -- 13. Accessing the genomes of uncultivated microbes for novel natural products / Asuncion Martinez, Joern Hopke, Ian A. MacNeil and Marcia S. Osburne -- 14. New natural-product diversity from marine actinomycetes / Paul R. Jensen and William Fenical -- 15. Novel natural products from rainforest endophytes / Gary Strobel, Bryn Daisy and Uvidelio Castillo -- 16. Biological, economic, ecological, and legal aspects of harvesting traditional medicine in ecuador / Alexandra Guevara-Aguirre and Ximena Chiriboga.
ISBN
  • 1588293831 (alk. paper)
  • 1592599206 (e-ISBN)
LCCN
2004026635
OCLC
  • ocm56956492
  • SCSB-5240992
Owning Institutions
Columbia University Libraries