Research Catalog

Title

Epstein-Barr virus / edited by Alex Tselis, Hal B. Jenson.

Publication

New York : Taylor & Francis, 2006.

Items in the Library & Off-site

Holdings

Details

Additional Authors

• Tselis, Alexandros Constantine, 1956-
• Jenson, Hal B.

Description

xviii, 406 pages : illustrations (some color); 27 cm.

Series Statement

Infectious disease and therapy ; 38

Uniform Title

Infectious disease and therapy ; v. 38.

Subjects

• Epstein-Barr Virus Infections
• Epstein-Barr Virus Infections > virology
• Lymphoproliferative Disorders
• Epstein-Barr virus diseases
• Herpesvirus 4, Human
• Epstein-Barr virus

Bibliography (note)

• Includes bibliographical references and index.

Contents

Foreword / George Miller -- 1. The History of Epstein-Barr Virus / Alex Tselis -- 2. Virology and Molecular Biology of Epstein-Barr Virus / Jeffrey I. Cohen -- Virus Structure and Genome -- Virus Replication -- Latent Infection -- Lytic Infection -- 3. Epidemiology of Primary Epstein-Barr Virus Infection and Infectious Mononucleosis / Warren A. Andiman -- Sources of Epidemiologic Data -- Descriptive Epidemiology -- 4. Pathology of Primary and Persistent Epstein-Barr Virus Infection / Gerald Niedobitek and Hermann Herbst -- Infectious Mononucleosis -- Persistent EBV Infection -- EBV Replication in Primary and Persistent Infection -- Fatal IM, CAEBV Infection, and EBV-AHS -- Expression of Cytokine and Chemokine Genes in IM and CAEBV Infection -- 5. The Immune Response to Epstein-Barr Virus / Scott R. Burrows and Andrew D. Hislop -- Humoral Response -- T-Cell Response During IM and After Resolution of Disease -- T-Cell Response in Asymptomatic Primary Infection -- T-Cell Response in Healthy Virus Carriers -- T-Cell-Mediated Control of EBV-Associated Tumors -- TCR Selection -- Concluding Remarks and Future Directions -- 6. Clinical Features of Infectious Mononucleosis / Jan Andersson -- Clinical Characterization of Acute Infectious Mononucleosis -- Atypical Presentations of Acute IM -- Acute Complications of EBV IM -- Therapy of Acute Infection -- 7. Epstein-Barr Virus Disease-Serologic and Virologic Diagnosis / Alex Tselis, Joseph R. Merline and Gregory A. Storch -- Heterophile Antibodies -- Conventional EBV Serologic Tests -- Determining EBV Status Based on Serological Panels -- Detection of EBV by Viral Culture -- Detection of EBV Genome -- Direct Detection of Latent EBV Infection -- Use of EBV Diagnostic Tests in Selected Clinical Circumstances -- 8. Epstein-Barr Virus and the Nervous System / Alex Tselis and Kumar Rajamani -- EBV-Related Neurological Diseases -- Treatment -- Relation Between EBV and MS -- 9. Epstein-Barr Virus and HIV / Richard F. Ambinder -- HIV Infection, EBV Antibody Responses, and EBV Copy Number -- Viral Strains in HIV-Infected Patients -- Non-Neoplastic Manifestations of EBV Infection in HIV-Infected Patients -- HIV and Lymphoma -- HIV and Other Malignancies -- EBV Detection and Clinical Decision Making -- Prevention of EBV-Associated Lymphoma -- Treatment of EBV-Associated Lymphoma -- 10. Burkitt Lymphoma / Jeffery T. Sample and Ingrid K. Ruf -- Classification and Characteristics of BL -- Infectious Cofactors -- Molecular Pathogenesis of BL -- EBV in BL-Causal Role or B-Cell Cohabitation? -- Prospects for Future Discovery -- 11. Epstein-Barr Virus Infection in Hodgkin Lymphomas / Hermann Herbst and Gerald Niedobitek -- Histology of HL -- Biology of HRS Cells -- EBV DNA and RNA in HLs -- EBV Antigen Expression in HLs -- EBV Infection and the Phenotype of HRS Cells -- HL and EBV-Specific Immunity -- 12. Posttransplant Lymphoproliferative Disorder / Lode J. Swinnen -- Epidemiology -- Pathology of PTLD -- Clinical Features and Management -- Early Diagnosis and Screening -- 13. T-Cell Lymphomas Associated with Epstein-Barr Virus / James F. Jones -- Types of T-Cell Lymphomas and Their Association with EBV -- 14. Nasopharyngeal Carcinoma / Sai Wah Tsao, Kwok Wai Lo and Dolly P. Huang -- EBV Gene Expression During Latent Infection -- Genetic Susceptibility of NPC -- Association of EBV Infection with NPC -- Genetic Alterations in NPC -- EBV Infection in Epithelial Cells and B Lymphocytes -- EBV Infection in Nasopharyngeal Epithelial Cells -- Transformation Properties of Gene Products Encoded by EBV -- Proposed Sequence of Events for NPC Development -- 15. Leiomyosarcoma / Hal B. Jenson -- Epidemiology -- Pathogenesis -- 16. X-Linked Lymphoproliferative Disease / Thomas A. Seemayer, Thomas G. Gross, Arpad Lanyi and Janos Sumegi -- The Discovery of the Disease -- The XLP Registry -- The Diagnosis of XLP -- Clinical Manifestations of XLP -- Genotype-Phenotype Correlation -- The Role of EBV Infection in XLP -- Treatment and Prognosis -- The XLP Gene -- The XLP Protein -- XLP Mutations -- 17. Diseases Possibly Associated with Epstein-Barr Virus / James F. Jones -- Laboratory Detection of EBV Infection -- Methodological Issues and Their Applications -- Clinical Illnesses -- Identification of EBV as a Potential Cause of Autoimmune Disease -- Synthesis -- 18. Treatment of Epstein-Barr Virus Infections: Chemotherapy, Antiviral Therapy, and Immunotherapy / Patrizia Comoli and Cliona Rooney -- Treatment of Diseases Associated with EBV Infection -- Prevention of EBV Infection or EBV-Associated Disease -- 19. The Development of Epstein-Barr Virus Vaccines / Andrew J. Morgan and A. Douglas Wilson -- What Is the Demand for EBV Vaccines? -- Progress with Other Human Herpesvirus Vaccines -- Several Alternative Objectives for EBV Vaccination -- GP350 Vaccines -- GP350 Vaccines and a Primate Model of EBV Lymphoma -- Peptide Vaccines -- Other Animal Models -- Human Trials -- Further Considerations in EBV Vaccine Design -- Possible Therapeutic Vaccination.

ISBN

0824754255 (alk. paper)

LCCN

• 2005054882
• 9780824754259

OCLC

• ocm62078261
• SCSB-5245595

Owning Institutions

Columbia University Libraries