Research Catalog

Introduction to randomized controlled clinical trials

Title
Introduction to randomized controlled clinical trials / John N.S. Matthews.
Author
Matthews, J. N. S.
Publication
Boca Raton, FL : Chapman & Hall/CRC, [2006], ©2006.
Supplementary Content
Publisher description

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Description
283 pages : illustrations; 24 cm.
Summary
"This second edition of Introduction to Randomized Controlled Clinical Trials provides a concise presentation of the principles applied in this area. It details the concepts behind randomization and methods for designing and analyzing trials and also includes information on meta-analysis and specialized designs, such as crossover trials, cluster-randomized designs, and equivalence studies." "This latest edition features new and revised references, examples exercises, and a new chapter dedicated to binary outcomes and survival analysis. It also presents numerous examples taken from the medical literature, contains exercises at the end of each chapter, and offers solutions in an appendix. The author used Minitab and R software throughout the text for implementing the methods that are presented."--BOOK JACKET.
Series Statement
Texts in statistical science
Uniform Title
Texts in statistical science.
Subjects
Bibliography (note)
  • Includes bibliographical references (p. 269-272) and index.
Contents
1. What is a randomized controlled trial? -- 2. Bias -- 3. How many patients do I need? -- 4. Methods of allocation -- 5. Assessment, blinding, and placebos -- 6. Analysis of results -- 7. Further analysis : binary and survival data -- 8. Monitoring accumulating data -- 9. Subgroups and multiple outcomes -- 10. Protocols and protocol deviations -- 11. Some special designs : crossovers, equivalence, and clusters -- 12. Meta-analyses of clinical trials.
ISBN
1584886242 (alk. paper)
LCCN
  • 2006042637
  • 9781584886242
OCLC
  • ocm64511342
  • SCSB-5267538
Owning Institutions
Columbia University Libraries