Research Catalog
Adaptive design methods in clinical trails
- Title
- Adaptive design methods in clinical trails / Shein-Chung Chow, Mark Chang.
- Author
- Chow, Shein-Chung, 1955-
- Publication
- Boca Raton : Chapman & Hall/CRC, [2007], ©2007.
Items in the Library & Off-site
Filter by
1 Item
| Status | Format | Access | Call Number | Item Location |
|---|---|---|---|---|
| Text | Request in advance | R853.C55 C53 2007 | Off-site |
Holdings
Details
- Additional Authors
- Chang, Mark.
- Description
- 277 pages : illustrations; 24 cm.
- Summary
- "One of the first books on the topic, Adaptive Design Methods in Clinical Trials presents the principles and methodologies in adaptive design and analysis the pertain to adaptations made to trial or statistical procedures that are based on accrued data of ongoing clinical trials. The book also offers a well-balanced summary of current regulatory perspectives and recently developed statistical methods in this area."--BOOK JACKET.
- Series Statement
- Chapman & Hall/CRC biostatistics series ; 17
- Uniform Title
- Chapman & Hall/CRC biostatistics series ; 17.
- Subjects
- Bibliography (note)
- Includes bibliographical references (p. [255]-267) and index.
- Contents
- 1. Introduction -- 2. Protocol amendment -- 3. Adaptive randomization -- 4. Adaptive hypotheses -- 5. Adaptive dose-escalation trials -- 6. Adaptive group sequential design -- 7. Adaptive sample size adjustment -- 8. Adaptive seamless phase II/III designs -- 9. Adaptive treatment switching -- 10. Bayesian approach -- 11. Clinical trial simulation -- 12. Case studies.
- ISBN
- 1584887761
- 9781584887768
- LCCN
- 2006048510
- OCLC
- ocm70408042
- SCSB-8856863
- Owning Institutions
- Columbia University Libraries